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The eutomer is the enantiomer having the desired pharmacological activity, [4] e.g., as an active ingredient in a drug. The distomer , on the other hand, is the enantiomer of the eutomer which may have undesired bioactivity or may be bio-inert.
One enantiomer of a drug may have a desired beneficial effect while the other may cause serious and undesired side effects, or sometimes even beneficial but entirely different effects. [1] The desired enantiomer is known as an eutomer while the undesired enantiomer is known as the distomer. [ 2 ]
An example of such an enantiomer is the sedative thalidomide, which was sold in a number of countries around the world from 1957 until 1961. It was withdrawn from the market when it was found to cause birth defects. One enantiomer caused the desirable sedative effects, while the other, unavoidably [23] present in equal quantities, caused birth ...
Chiral purity is a measure of the purity of a chiral drug. Other synonyms employed include enantiomeric excess, enantiomer purity, enantiomeric purity, and optical purity. Optical purity is an obsolete term since today most of the chiral purity measurements are done using chromatographic techniques (not based on optical principles).
In chemistry, racemization is a conversion, by heat or by chemical reaction, of an optically active compound into a racemic (optically inactive) form. This creates a 1:1 molar ratio of enantiomers and is referred to as a racemic mixture (i.e. contain equal amount of (+) and (−) forms).
Get ready for all of today's NYT 'Connections’ hints and answers for #549 on Wednesday, December 11, 2024. Today's NYT Connections puzzle for Wednesday, December 11, 2024 The New York Times
Get ready for all of today's NYT 'Connections’ hints and answers for #579 on Friday, January 10, 2025. Today's NYT Connections puzzle for Friday, January 10, 2025 The New York Times
In today's puzzle, there are six theme words to find (including the spangram). Hint: The first one can be found in the top-half of the board. Here are the first two letters for each word: