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In men over 30 and women over 50, rates are 2%. [92] In the United States, gout is twice as likely in males of African descent than those of European descent. [107] Rates are high among Polynesians, but the disease is rare in aboriginal Australians, despite a higher mean uric acid serum concentration in the latter group. [108]
Gout in foot joints is most common, with gout often affecting the big toe joint. However, other joints can be affected as well, particularly those in the lower body. For example, gout in ankles or ...
Nail psoriasis can affect the fingernails and toenails. It may cause thickening of the nails with areas of pitting, ridges, irregular contour, and even raising of the nail from the nail bed. [16] Squamous-cell carcinoma is mainly cancer of the skin, but can also affect the nail bed. It is a rare malignant subungual tumor subject to misdiagnosis ...
Excess blood uric acid (serum urate) can induce gout, [44] a painful condition resulting from needle-like crystals of uric acid termed monosodium urate crystals [45] precipitating in joints, capillaries, skin, and other tissues. [46] Gout can occur where serum uric acid levels are as low as 6 mg per 100 mL (357 μmol/L), but an individual can ...
Nail clubbing, also known as digital clubbing or clubbing, is a deformity of the finger or toe nails associated with a number of diseases, anomalies and defects, some congenital, mostly of the heart and lungs. [2] [3] When it occurs together with joint effusions, joint pains, and abnormal skin and bone growth it is known as hypertrophic ...
The drug is the first line treatment for ovarian, breast, lung, and colon cancer and the second line treatment for AIDS-related Kaposi's sarcoma. (Kaposi sarcoma is a cancer of the skin and mucous membranes that is commonly found in patients with acquired immunodeficiency syndrome, AIDS).
While men, since the later 1900s and particularly in the ’90s, have had a higher cancer incidence than women, incidence rates in women 50-64 years of age have now surpassed those in men.
Colchicine is typically prescribed to mitigate or prevent the onset of gout, or its continuing symptoms and pain, using a low-dose prescription of 0.6 to 1.2 mg per day, or a high-dose amount of up to 4.8 mg in the first 6 hours of a gout episode. [14] [26] With an oral dose of 0.6 mg, peak blood levels occur within one to two hours. [50]