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Cause of death disputed, but syphilis or mercury poisoning from syphilis treatment are leading theories. Franz Schubert (1797–1828), German composer Cause of death disputed, but symptoms match to mercury poisoning from syphilis treatment. [10] Robert Schumann (1810–1856), German composer Acquired syphilis from a prostitute in the age of 21 ...
Wagner-Jauregg (center right in black jacket) watching a transfusion from a malaria patient (rear of the group) to a neurosyphilis victim (center) in 1934. The main work pursued by Wagner-Jauregg throughout his life was related to the treatment of mental disease by inducing a fever, an approach known as pyrotherapy.
Hideyo Noguchi (野口 英世, Noguchi Hideyo, November 9, 1876 – May 21, 1928), also known as Seisaku Noguchi (野口 清作, Noguchi Seisaku), was a prominent Japanese bacteriologist at the Rockefeller Institute known for his work on syphilis, yellow fever, antivenom, and Rocky Mountain spotted fever and contributing to the long term understanding of neurosyphilis.
In the infant stages of this disease in Europe, many ineffective and dangerous treatments were used. The aim of treatment was to expel the foreign, disease-causing substance from the body, so methods included blood-letting, laxative use, and baths in wine and herbs or olive oil. [64] Mercury was a common, long-standing treatment for syphilis. [65]
Another late form of neurosyphilis is general paresis, which is a slow degenerative process of the brain. Neuropsychiatric symptoms might appear due to overall damage to the brain. These symptoms can make the diagnosis more difficult and can include symptoms of dementia, [11] [12] mania, psychosis, depression, [13] and delirium. [14]
In those with neurosyphilis, intravenous benzylpenicillin or ceftriaxone is recommended. [4] During treatment, people may develop fever, headache, and muscle pains, a reaction known as Jarisch–Herxheimer. [4] In 2015, about 45.4 million people had syphilis infections, [5] of which six million were new cases. [9]
Seventy-four percent were using Suboxone to ease withdrawal symptoms while sixty-four percent were using it because they couldn’t afford drug treatment. The researchers noted: “Common reasons given for not being currently enrolled in a buprenorphine/naloxone program included cost and unavailability of prescribing physicians.”
Meningeal syphilis (as known as syphilitic aseptic meningitis or meningeal neurosyphilis) is a chronic form of syphilis infection that affects the central nervous system. Treponema pallidum , a spirochate bacterium, is the main cause of syphilis, which spreads drastically throughout the body and can infect all its systems if not treated ...