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  2. Prion - Wikipedia

    en.wikipedia.org/wiki/Prion

    A prion / ˈ p r iː ɒ n / ⓘ is a misfolded protein that induces misfolding in normal variants of the same protein, leading to cellular death.Prions are responsible for prion diseases, known as transmissible spongiform encephalopathy (TSEs), which are fatal and transmissible neurodegenerative diseases affecting both humans and animals.

  3. Viral replication - Wikipedia

    en.wikipedia.org/wiki/Viral_replication

    Viruses may undergo two types of life cycles: the lytic cycle and the lysogenic cycle. In the lytic cycle, the virus introduces its genome into a host cell and initiates replication by hijacking the host's cellular machinery to make new copies of the virus. [12] In the lysogenic life cycle, the viral genome is incorporated into the host genome.

  4. Major prion protein - Wikipedia

    en.wikipedia.org/wiki/Major_prion_protein

    The abnormal protein PrP Sc accumulates in the brain and destroys nerve cells, which leads to the mental and behavioral features of prion diseases. [citation needed] Several other changes in the PRNP gene (called polymorphisms) do not cause prion diseases but may affect a person's risk of developing these diseases or alter the course of the ...

  5. Protein misfolding cyclic amplification - Wikipedia

    en.wikipedia.org/wiki/Protein_misfolding_cyclic...

    PMCA was originally developed to, in vitro, mimic prion replication with a similar efficiency to the in vivo process, but with accelerated kinetics. [1] PMCA is conceptually analogous to the polymerase chain reaction - in both systems a template grows at the expense of a substrate in a cyclic reaction, combining growing and multiplication of the template units.

  6. Lytic cycle - Wikipedia

    en.wikipedia.org/wiki/Lytic_cycle

    Once the viral DNA has taken control it induces the host cell's machinery to synthesize viral DNA and proteins and begins to multiply. [citation needed] The biosynthesis is (e.g. T4) regulated in three phases of mRNA production followed by a phase of protein production. [3] Early phase Enzymes modify the host's transcriptional process by RNA ...

  7. Self-replication - Wikipedia

    en.wikipedia.org/wiki/Self-replication

    Self-replication is a fundamental feature of life. It was proposed that self-replication emerged in the evolution of life when a molecule similar to a double-stranded polynucleotide (possibly like RNA) dissociated into single-stranded polynucleotides and each of these acted as a template for synthesis of a complementary strand producing two double stranded copies. [4]

  8. AOL Mail

    mail.aol.com/?rp=webmail-std/en-us/basic

    Get AOL Mail for FREE! Manage your email like never before with travel, photo & document views. Personalize your inbox with themes & tabs. You've Got Mail!

  9. Poliovirus - Wikipedia

    en.wikipedia.org/wiki/Poliovirus

    Poliovirus, the causative agent of polio (also known as poliomyelitis), is a serotype of the species Enterovirus C, in the family of Picornaviridae. [1] There are three poliovirus serotypes, numbered 1, 2, and 3.