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SGLT2 inhibitors cause the loss of 60–100 grams (2.1–3.5 oz) glucose in the urine each day and are associated with a modest, sustained weight loss of 1.5–2 kilograms (3.3–4.4 lb) in people with type 2 diabetes.
Bicalutamide is used primarily in the treatment of early and advanced prostate cancer. [1] It is approved at a dosage of 50 mg/day as a combination therapy with a gonadotropin-releasing hormone analogue (GnRH analogue) or orchiectomy (that is, surgical or medical castration) in the treatment of stage D2 metastatic prostate cancer (mPC), [2] [3] and as a monotherapy at a dosage of 150 mg/day ...
For most people, 3.5 dried grams (1/8 oz) would be considered a high dose and may produce an intense experience; this is, however, typically considered a standard dose among recreational users. Body composition (usually weight) should be taken into account when calculating dosage. For many individuals, doses above three grams may be overwhelming.
Polonium in the body has a biological half-life of about 30 to 50 days. Caesium in the body has a biological half-life of about one to four months. Mercury (as methylmercury) in the body has a half-life of about 65 days. Lead in the blood has a half life of 28–36 days. [29] [30] Lead in bone has a biological half-life of about ten years.
[86] [7] With a 10 mg oral dose of selegiline, about 2 to 6 mg levomethamphetamine and 1 to 3 mg levoamphetamine is excreted in urine. [7] [89] [86] [90] As levoamphetamine and levomethamphetamine are norepinephrine and/or dopamine releasing agents, they may contribute to the effects and side effects of selegiline.
Jamie Dimon says the next generation of employees will work 3.5 days a week and live to 100 years old ... adding that artificial intelligence is a “living breathing thing” that will shift over ...
Psilocybin comprises approximately 1% of the weight of Psilocybe cubensis mushrooms, and so nearly 1.7 kilograms (3.7 lb) of dried mushrooms, or 17 kilograms (37 lb) of fresh mushrooms, would be required for a 60-kilogram (130 lb) person to reach the 280 mg/kg LD 50 value of rats. [46]
The lethal risk from one dose of MDMA is estimated to be from 1 death in 20,000 instances to 1 death in 50,000 instances. [ 31 ] Short-term adverse effects include grinding of the teeth , blurred vision , sweating , and a rapid heartbeat , [ 25 ] and extended use can also lead to addiction, memory problems , paranoia , and difficulty sleeping .