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Finasteride is a 5α-reductase inhibitor and therefore an antiandrogen. [10] It works by decreasing the production of dihydrotestosterone (DHT) by about 70%. [6] In addition to DHT, finasteride also inhibits the production of several anticonvulsant neurosteroids including allopregnanolone, androstanediol, and tetrahydrodeoxycorticosterone. [11]
5α-Reductase inhibitors (5-ARIs), also known as dihydrotestosterone (DHT) blockers, are a class of medications with antiandrogenic effects which are used primarily in the treatment of enlarged prostate and scalp hair loss. They are also sometimes used to treat excess hair growth in women and as a component of hormone therapy for transgender ...
Beta-blockers. Quick disclaimer: ... Finasteride. This medication targets the hormone dihydrotestosterone , which contributes to male pattern baldness (AKA androgenic alopecia).
Commonly prescribed beta-blockers include propranolol, atenolol, metoprolol, timolol, nadolol and others. ... Another hair growth medication called finasteride is an FDA-approved medication that ...
This is a list of 5α-reductase inhibitors (5α-RIs), drugs which inhibit one or more isoforms of the enzyme 5α-reductase.This enzyme is responsible for the conversion of the androgen hormone testosterone into the more potent dihydrotestosterone (DHT) and is essential for the production of neurosteroids like allopregnanolone, tetrahydrodeoxycorticosterone (THDOC), and 3α-androstanediol from ...
Finasteride is the active ingredient in Propecia®, an oral medication that’s clinically-proven to treat and prevent male pattern baldness. ... 5-alpha reductase blockers reduce DHT levels ...
Dutasteride (Avodart) was the second steroidal 5α-reductase approved after finasteride. It is a competitive inhibitor of all three 5α-reductase isoenzymes [4] and it inhibits types 1 and 2 better than finasteride, leading to it causing further reduction in DHT, with >90% recuded DHT levels following 1 year of oral administration. [1]
Finasteride is the most well-known science-backed DHT blocker. Natural DHT blockers, like saw palmetto and pumpkin seed oil, aren’t as rigorously studied as finasteride. You can combine treatments.