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Kratom overdose is a subject of concern in many countries because of the associated rising number of hospitalizations and deaths in which chronic kratom use is a contributing factor. [11] [16] According to clinical reviews, a kratom overdose can cause liver toxicity, seizures, coma, and death, [16] especially in combination with excessive ...
In Thai varieties of kratom, mitragynine is the most abundant component (up to 66% of total alkaloids), while 7-hydroxymitragynine (7-OH) is a minor constituent (up to 2% of total alkaloid content). In Malaysian kratom varieties, mitragynine is present at lower concentration (12% of total alkaloids). [5]
7-Hydroxymitragynine (7-OH) is a terpenoid indole alkaloid from the plant Mitragyna speciosa, commonly known as kratom. [2] It was first described in 1994 [3] and is a human metabolite metabolized from mitragyna speciosa present in the kratom leaf. 7-OH binds to opioid receptors like mitragynine, but research suggests that 7-OH binds with greater efficacy.
High blood pressure is caused by the force of blood flow in the arteries being too high. The DASH diet includes heart-healthy foods that lower blood pressure.
Dark chocolate is rich in flavanols, a natural compound that can lower blood pressure, reducing the risk of stroke and heart disease, adds Frances Largeman-Roth, a registered dietitian. She ...
Kratom, or mitragyna speciosa, is a tree that grows naturally in Southeast Asia, where it’s been used for centuries, and can be consumed in a variety of ways. In the U.S., products containing ...
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