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Interstate 26. Connecting directly from I-81, I-26 offers another major corridor for travel between East Tennessee and the Carolinas. Motorists can use this route to travel south from I-81 toward ...
U.S. Route 441 (US 441) is a north–south United States Highway that runs from Miami, Florida to Rocky Top, Tennessee.In the U.S. state of North Carolina, US 441 travels for 64.5 miles (103.8 km) from the Georgia state line near Dillard, Georgia to the Tennessee state line in the Great Smoky Mountains National Park.
US 441 merges with US 23, remaining concurrent with the route through Clayton (where US 23 and US 441 are concurrent with U.S. Route 76 for a short distance) into North Carolina. The portion of US 23 / US 441 from U.S. Route 123 west of Toccoa to the North Carolina state line is located within the Chattahoochee National Forest .
U.S. Route 421 (also U.S. Highway 421, US 421) is a diagonal northwest–southeast United States Numbered Highway in the states of North Carolina, Tennessee, Virginia, Kentucky, and Indiana. The highway runs for 941 miles (1,514 km) from Fort Fisher, North Carolina, to US 20 in Michigan City, Indiana.
I-40 / I-275 – Nashville, Asheville, NC, Lexington, KY: I-40 exit 388; I-275 exit 0A: SR 62 west (Western Avenue) – Karns, Oak Ridge: Eastern terminus of SR 62: West Fifth Avenue – Asheville, NC: Former northern end of US 11/US 70/SR 1 concurrency; SR 33 turns primary: Hall of Fame Drive (unsigned SR 71 south)
U.S. Route 76 (US 76) is an east–west U.S. highway in the Southeastern United States that travels for 548 miles (882 km). Its western terminus is at US 41 and the eastern terminus of US 72 (Broad Street) in the city of Chattanooga, Tennessee, where it travels in a generally due east direction, to its eastern terminus at Wrightsville Beach, North Carolina.
US 129 south (Calderwood Highway / SR 115) – Fontana, NC, Robbinsville, NC: Southern end of US 129 concurrency; provides access to the Tail of the Dragon: Maryville: 69.4: 111.7: SR 335 north (William Blount Drive) Southern terminus of SR 335: 72.4: 116.5: US 129 north / US 411 Truck north (Alcoa Highway / SR 115) – Knoxville, Alcoa
The Clayton Bypass is a four-lane freeway that is 9.8 miles (15.8 km) in length south of Clayton. Starting west of Clayton at a turbine interchange with I-40 and NC 540 on the Wake–Johnston county line, it continues southeast and connects with NC 42 and Ranch Road, before reaching an interchange with US 70/US 70 Bus., where US 70 merges into the through traffic.
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