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Chronic hyperglycemia (high blood sugar) injures the heart in patients without a history of heart disease or diabetes and is strongly associated with heart attacks and death in subjects with no coronary heart disease or history of heart failure. [26] Also, a life-threatening consequence of hyperglycemia can be nonketotic hyperosmolar syndrome. [20]
The complications of diabetes can dramatically impair quality of life and cause long-lasting disability. Overall, complications are far less common and less severe in people with well-controlled blood sugar levels. [3] [4] [5] Some non-modifiable risk factors such as age at diabetes onset, type of diabetes, gender, and genetics may influence risk.
This leads to excessive urination (more specifically an osmotic diuresis), which, in turn, leads to volume depletion and hemoconcentration that causes a further increase in blood glucose level. Ketosis is absent because the presence of some insulin inhibits hormone-sensitive lipase -mediated fat tissue breakdown .
Diabetes can also cause a condition called hypoglycemia, a.k.a. low blood sugar. This may happen when you miss a meal, are physically active close to bedtime, or drink alcohol at night, according ...
Other conditions that can cause unconsciousness in a person with diabetes are stroke, uremic encephalopathy, alcohol, drug overdose, head injury, or seizure. Most patients do not reach the point of unconsciousness or coma in cases of diabetic hypoglycemia, diabetic ketoacidosis, or severe hyperosmolarity before a family member or caretaker ...
Hyperosmolar syndrome or diabetic hyperosmolar syndrome is a medical emergency caused by a very high blood glucose level. The prefix " hyper- " means high, and " osmolarity " is a measure of the concentration of active particles in a solution , so the name of the syndrome simply refers to the high concentration of glucose in the blood .
This resulting hyperglycemia is clinically relevant in diabetic patients as its lasting effects can lead to overall poor glycemic control. In Type 1 diabetics hyperglycemia due to the dawn phenomenon can persist despite adequate insulin compensation overnight, while in Type 2 diabetics the dawn phenomenon has been shown to be resistant to ...
Diabetic neuropathy can affect any peripheral nerves including sensory neurons, motor neurons, and the autonomic nervous system. Therefore, diabetic neuropathy has the potential to affect essentially any organ system and can cause a range of symptoms. There are several distinct syndromes based on the organ systems affected. [citation needed]
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