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Thick smears allow the microscopist to screen a larger volume of blood and are about eleven times more sensitive than the thin film, so picking up low levels of infection is easier on the thick film, but the appearance of the parasite is much more distorted and therefore distinguishing between the different species can be much more difficult.
A human peripheral blood smear; NRBCs are visible as larger cells with dark centers.. A nucleated red blood cell (NRBC), also known by several other names, is a red blood cell that contains a cell nucleus.
This is a trashy smear, but it does show an extremely advanced case of the microcytic/hypochromic anemia characteristic of iron deficiency. The mean corpuscular volume (MCV) was 55 fL (reference range: 80 - 94 fL). Pathological and histological images courtesy of Ed Uthman at flickr. Date: 8 March 2010, 16:35: Source
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Rare elliptocytes (less than 1%) on a peripheral blood smear are a normal finding. [citation needed] These abnormal red blood cells are seen in higher numbers in the blood films of patients with blood disorders such as: [4] Hereditary elliptocytosis and Southeast Asian ovalocytosis; Thalassemia; Iron deficiency; Myelodysplastic syndrome and ...
Hemolytic anemia or haemolytic anaemia is a form of anemia due to hemolysis, the abnormal breakdown of red blood cells (RBCs), either in the blood vessels (intravascular hemolysis) or elsewhere in the human body (extravascular). [2]
Peripheral blood smear in patient with thrombotic thrombocytopenic purpura. Typical schistocytes are annotated. A schistocyte or schizocyte (from Greek schistos for "divided" and kytos for "hollow" or "cell") is a fragmented part of a red blood cell. Schistocytes are typically irregularly shaped, jagged, and have two pointed ends. [1]