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With regard to morphology, the initial lesion that characterizes a condition is known as the "primary lesion", and identification of such a lesions is the most important aspect of the cutaneous examination. [30] Over time, these primary lesions may continue to develop or be modified by regression or trauma, producing "secondary lesions". [1]
Chancre on a penis due to primary syphilis, 1978. Primary syphilis is typically acquired by direct sexual contact with the infectious lesions of another person. [19] Approximately 2–6 weeks after contact (with a range of 10–90 days) a skin lesion, called a chancre, appears at the site and this contains infectious bacteria.
After primary and secondary yaws (and possibly, in some cases, without these phases), a latent infection develops. [2] Within five years (rarely, within ten years [2]) it can relapse and become active again, causing further secondary lesions, which may infect others. [12] These relapse lesions are most commonly found around the armpits, mouth ...
What it looks like: Purplish lesions on the inner arms, legs, wrists, or ankles can signify lichen planus, a skin rash triggered by an overreaction of the immune system.
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]
Areas of the skin exposed to friction and radiation are typically affected first. [1] Over time affected skin may become darker, stiffen, peel, or bleed. [1] [3] There are two main types of pellagra, primary and secondary. [1] Primary pellagra is due to a diet that does not contain enough niacin and tryptophan. [1]
Cutaneous B-cell lymphomas (CBCL), more recently termed Primary cutaneous B-cell lymphomas and lymphoproliferative disorders (PCBCLPD), are a group of disorders that typically present as skin lesions consisting of proliferating B-cells. B-cells are a type of lymphocyte involved in regulating immune responses.
Certain endogenous substances, like uric acid in uremia, biliary salts in pregnancy or hepatobiliary cirrhosis, or histamine in atopic patients, can occasionally cause local reactions in the skin that result in prurigo lesions that are identical to the primary lesion of acute, subacute, or chronic prurigo. There are several types of prurigo ...