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About 10 million people globally live with inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn’s disease. ... under review with the U.S. FDA for moderately to severely ...
The anti-TNF-α monoclonal antibody infliximab is a major biological therapy for inflammatory bowel disease. Biological therapy, the use of medications called biopharmaceuticals or biologics that are tailored to specifically target an immune or genetic mediator of disease, plays a major role in the treatment of inflammatory bowel disease. [1]
Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine, with Crohn's disease and ulcerative colitis (UC) being the principal types. [3] Crohn's disease affects the small intestine and large intestine, as well as the mouth, esophagus, stomach and the anus, whereas UC primarily affects the colon ...
Obesity, which creates ongoing, chronic inflammation in the body, is increasingly associated with inflammatory bowel disease (IBD) and may negatively influence the disease course.
Inflammatory Bowel Diseases is a monthly peer-reviewed medical journal covering all aspects of inflammatory bowel disease. It was established in 1995 and is published by Oxford University Press. [1] It is the official journal of the Crohn's & Colitis Foundation. The editor-in-chief is Fabio Cominelli (Case Western Reserve University). [2]
Acupuncture is used to treat inflammatory bowel disease in China, and is being used more frequently in Western society. [38] Evidence has been put forth suggesting that acupuncture can have benefits beyond the placebo effect, improving quality of life, general well-being and a small decrease in blood-bound inflammatory markers. [38]
Ulcerative colitis (UC) is one of the two types of inflammatory bowel disease (IBD), with the other type being Crohn's disease. [1] It is a long-term condition that results in inflammation and ulcers of the colon and rectum. [1] [7] The primary symptoms of active disease are abdominal pain and diarrhea mixed with blood (hematochezia). [1]
Treatment of immune checkpoint inhibitor colitis is based on severity, as defined by the grade of diarrhea and colitis. Mild cases by managed with temporary interruption of immune checkpoint inhibitor therapy, dietary modification (low residue), and/or loperamide. More severe cases require immune suppression with corticosteroid therapy.
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