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Metolazone is a thiazide-like diuretic marketed under the brand names Zytanix, Metoz, Zaroxolyn, and Mykrox. It is primarily used to treat congestive heart failure and high blood pressure . Metolazone indirectly decreases the amount of water reabsorbed into the bloodstream by the kidney , so that blood volume decreases and urine volume increases.
Here are links to possibly useful sources of information about Metolazone. PubMed provides review articles from the past five years (limit to free review articles) The TRIP database provides clinical publications about evidence-based medicine. Other potential sources include: Centre for Reviews and Dissemination and CDC
Thank you for your thoughtful review! I explained about thiazides, moved sulfonamide allergy to toxicity, and put the date accessed on the links. I'll do my best with the history, although history is notoriously difficult—especially for medical topics, where "history" has a special meaning and severly confounds searches.
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