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Retinol-binding protein 4 has been a drug target for eye diseases as RBP4 is the sole carrier for retinol, which is an essential nutrient for the visual cycle. Animal studies using RBP4-antagonists showed that lowering RBP4 can lead to reduction in the accumulation of lipofuscin that leads to vision loss in eye diseases like Stargardt's disease ...
Plasma retinol-binding protein, the retinol transport vehicle in serum. [13] CRBP I/II, cellular-binding proteins involved in transport of retinol and metabolites into retinyl esters for storage or into retinoic acid. [14] CRABPs, cellular retinoic acid–binding proteins capable of binding retinol and retinoic acid with high affinity.
5928 19646 Ensembl ENSG00000162521 ENSMUSG00000057236 UniProt Q09028 Q60972 RefSeq (mRNA) NM_005610 NM_001135255 NM_001135256 NM_009030 RefSeq (protein) NP_001128727 NP_001128728 NP_005601 NP_033056 Location (UCSC) Chr 1: 32.65 – 32.69 Mb Chr 4: 129.2 – 129.23 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Histone-binding protein RBBP4 (also known as RbAp48, or NURF55) is a ...
It is a retinol binding protein 4 antagonist. [2] References This page was last edited on 11 September 2024, at 00:05 (UTC). Text is ...
In 2014, Wong’s son completed a clinical trial that increased his allergen tolerance from 1 mg to 1,440 mg of peanut protein, or about six peanuts. Although the family still avoids peanuts and ...
Hepatocytes take up the lipid-rich chylomicrons, bind retinol to retinol-binding protein 4 (RBP4), and transfer the retinol-RBP4 to HSCs for storage in lipid droplets as retinyl esters. Mobilization reverses the process: retinyl ester hydrolase releases free retinol which is transferred to hepatocytes, bound to RBP4, and put into blood ...
A high-protein diet helped me lose 35 pounds and stay in shape for six years. I use my '4/5' rule to hit my protein target without tracking. Staple foods like chicken, Greek yogurt, and chickpeas ...
“Frozen or canned artichokes provide a convenient and easy source of fiber to add to pasta dishes, grain bowls or even protein dishes,” says Meggie Connelly, M.S., RDN, LDN. Related: 18 ...
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