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Human microbiota are microorganisms (bacteria, viruses, fungi and archaea) found in a specific environment. They can be found in the stomach, intestines, skin, genitals and other parts of the body. [1] Various body parts have diverse microorganisms. Some microbes are specific to certain body parts and others are associated with many microbiomes.
Gut microbiota, gut microbiome, or gut flora are the microorganisms, including bacteria, archaea, fungi, and viruses, that live in the digestive tracts of animals. [ 1 ] [ 2 ] The gastrointestinal metagenome is the aggregate of all the genomes of the gut microbiota .
A significant quantity of the cellulose humans consume is not metabolized by gut microbes and therefore cannot be considered a MAC. [2] The amount of dietary MACs found within a food source will differ for each individual, since which carbohydrates are metabolized depends upon the composition of each person's microbiota.
The bacteria and fungi live together in the gut and there is most likely a competition for nutrient sources present. [ 99 ] [ 100 ] Seelbinder et al . found that commensal bacteria in the gut regulate the growth and pathogenicity of Candida albicans by their metabolites, particularly by propionate, acetic acid and 5-dodecenoate. [ 98 ]
Microbes can promote the development of the host's immune system in the gut and skin, and may help to prevent pathogens from invading. Some release anti-inflammatory products, protecting against parasitic gut microbes. Commensals promote the development of B cells that produce a protective antibody, Immunoglobulin A (IgA).
The manipulation of the gut microbiota is complex and may cause bacteria-host interactions. [5] Though probiotics are considered safe, some have concerns about their safety in certain cases. [ 5 ] [ 41 ] Some people, such as those with immunodeficiency , short bowel syndrome , central venous catheters , and cardiac valve disease , and premature ...
Microbial metabolism is the means by which a microbe obtains the energy and nutrients (e.g. carbon) it needs to live and reproduce.Microbes use many different types of metabolic strategies and species can often be differentiated from each other based on metabolic characteristics.
Human interactions with microbes include both practical and symbolic uses of microbes, and negative interactions in the form of human, domestic animal, and crop diseases. Practical use of microbes began in ancient times with fermentation in food processing ; bread , beer and wine have been produced by yeasts from the dawn of civilisation, such ...