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Aqueous Cream BP, also known as sorbolene, is a light, hydrocarbon-based emulsion, which is officially registered in the British Pharmacopoeia and categorised by the British National Formulary as a non-proprietary emollient preparation. [1]
Topical cream formulation is an emulsion semisolid dosage form that is used for skin external application. Most of the topical cream formulations contain more than 20 per cent of water and volatiles and/or less than 50 per cent of hydrocarbons , waxes , or polyethylene glycols as the vehicle for external skin application. [ 1 ]
Methyl cellulose (or methylcellulose) is a compound derived from cellulose.It is sold under a variety of trade names and is used as a thickener and emulsifier in various food and cosmetic products, and also as a bulk-forming laxative.
[5] [7] The solvent that is used as a dispersion medium can be aqueous, organic, inorganic, or a system of different solvents. [5] Topical gels are used as a contact or transport medium for active drugs to act on [4] or through the skin. [9] The active drug molecules are entwined into the 3D mesh of the gel and delivered to the site of action.
A study conducted in 1994 suggests menthol and camphor are effective cough suppressants for guinea pigs. [11] It has been suggested that thymol oil can reduce or cure onychomycosis (nail fungus), although the same source mentions that "no human studies have been conducted to test whether thymol is a lasting and effective treatment". [ 12 ]
Similarly, acne vulgaris is responsible for 3.5 million doctor visits each year in the United Kingdom. [20] Sales for the top ten leading acne treatment brands in the US in 2015 amounted to $352 million. [217] Acne vulgaris and its resultant scars are associated with significant social and academic difficulties that can last into adulthood.
Relief of skin pain caused by sunburn, ingrown toenails, hemorrhoids, [5] Examples of combination medications of benzocaine include: Antipyrine-benzocaine otic consists of antipyrine and benzocaine, and is used to relieve ear pain and remove earwax. [6] Cepacol consists of menthol and benzocaine, and is used to treat sore throat. [7]
[4] [5] It may also help dry out secretions resulting from skin irritation. [1] It is applied on the skin as a cream or lotion. [2] Side effects may include skin irritation. [4] It is considered to be safe in pregnancy. [4] Calamine is a combination of zinc oxide and 0.5% ferric oxide (Fe 2 O 3). [6]
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