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Tissue engineering of oral mucosa combines cells, materials and engineering to produce a three-dimensional reconstruction of oral mucosa. It is meant to simulate the real anatomical structure and function of oral mucosa. Tissue engineered oral mucosa shows promise for clinical use, such as the replacement of soft tissue defects in the oral ...
A set of human teeth under an orthopantomogram. Tooth regeneration is a stem cell based regenerative medicine procedure in the field of tissue engineering and stem cell biology to replace damaged or lost teeth by regrowing them from autologous stem cells.
A successful tissue regeneration relies on an appropriate source of stem progenitor cells, growth factors and scaffolds to control the development of the specific tissue. [19] The first component for tissue engineering is an appropriate source of progenitor/stem cells by using cells which are able to differentiate into the desired tissue component.
At present, guided bone regeneration is predominantly applied in the oral cavity to support new hard tissue growth on an alveolar ridge to allow stable placement of dental implants. When bone grafting is used in conjunction with sound surgical technique, guided bone regeneration is a reliable and validated procedure.
Micro-mass cultures of C3H-10T1/2 cells at varied oxygen tensions stained with Alcian blue. A commonly applied definition of tissue engineering, as stated by Langer [3] and Vacanti, [4] is "an interdisciplinary field that applies the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain, or improve [Biological tissue] function or a ...
Alastair has authored several books and book chapters in his field, as well as having his research widely published in leading medical, dental, tissue engineering and health policy journals including the Journal of Dental Research, The International Journal of Nanomedicine, BioMed Research International and The European Journal of Dental Education.
Dental pulp stem cells (DPSCs) are stem cells present in the dental pulp, which is the soft living tissue within teeth. DPSCs can be collected from dental pulp by means of a non-invasive practice. It can be performed with an adult after simple extraction or to the young after surgical extraction of wisdom teeth. [1]
The Journal of Tissue Engineering is a peer-reviewed open-access medical journal that covers research on tissue engineering. Its editors-in-chief are Hae-Won Kim (Dankook University) and Jonathan Knowles (UCL Eastman Dental Institute). It was established in 2010 and is published by SAGE Publications.