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  2. For people with sickle cell disease, ERs can mean life ... - AOL

    www.aol.com/news/people-sickle-cell-disease-ers...

    A sickle cell health crisis can escalate into life-threatening complications, but patients still struggle to get seen quickly in emergency rooms and also to get pain medicine.

  3. Sickle cell disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_disease

    Sickle cell disease (SCD), also simply called sickle cell, is a group of hemoglobin-related blood disorders that are typically inherited. [2] The most common type is known as sickle cell anemia. [2] Sickle cell anemia results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells. [2]

  4. Splenic infarction - Wikipedia

    en.wikipedia.org/wiki/Splenic_infarction

    In sickle cell disease, repeated splenic infarctions lead to a non-functional spleen (autosplenectomy). Any factor that directly compromises the splenic artery can cause infarction. Examples include abdominal traumas, aortic dissection , torsion of the splenic artery (for example, in wandering spleen ) or external compression on the artery by a ...

  5. Transfusion therapy (Sickle-cell disease) - Wikipedia

    en.wikipedia.org/wiki/Transfusion_therapy...

    It is used to treat life-threatening complications of sickle cell disease such as stroke or acute chest crisis. [4] There are three main benefits of an exchange transfusion compared to a simple transfusion, these relate primarily to the ability to remove hemoglobin S containing red blood cells: [5]

  6. FDA approves cure for sickle cell disease, the first ... - AOL

    www.aol.com/news/fda-approves-cure-sickle-cell...

    The FDA approved a new treatment for sickle cell disease. The therapy is first to use the ground-editing tool CRISPR. ... he is happy to be living a life free of chronic pain.

  7. Pfizer withdraws sickle cell disease treatment on risk of ...

    www.aol.com/news/pfizer-withdraws-sickle-cell...

    The company added that the data showed an imbalance in vaso-occlusive crises, a complication of the disease and "fatal events" that required further a. Pfizer bought Oxbryta, also known as ...

  8. Vaso-occlusive crisis - Wikipedia

    en.wikipedia.org/wiki/Vaso-occlusive_crisis

    A vaso-occlusive crisis is a common painful complication of sickle cell anemia in adolescents and adults. [1] [2] It is a form of sickle cell crisis.Sickle cell anemia – most common in those of African, Hispanic, and Mediterranean origin – leads to sickle cell crisis when the circulation of blood vessels is obstructed by sickled red blood cells, causing ischemic injuries.

  9. A new cure for sickle cell disease may be coming. FDA ... - AOL

    www.aol.com/cure-sickle-cell-disease-may...

    The only cure for painful sickle cell disease today is a bone marrow transplant. But soon there may be a new cure that attacks the disorder at its genetic source. On Tuesday, advisers to the Food ...