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It occurs when exposure to a substance – specifically, a neurotoxin or neurotoxicant– alters the normal activity of the nervous system in such a way as to cause permanent or reversible damage to nervous tissue. [1] This can eventually disrupt or even kill neurons, which are cells that transmit and process signals in the brain and other ...
The internal wall of the canal is very delicate and allows the fluid to filter due to the high pressure of the fluid within the eye. [7] The secondary route is the uveoscleral drainage , and is independent of the intraocular pressure, the aqueous flows through here, but to a lesser extent than through the trabecular meshwork (approx. 10% of the ...
Exposure to lower concentrations can result in eye irritation, a sore throat and cough, nausea, shortness of breath, and fluid in the lungs. [59] These effects are believed to be due to hydrogen sulfide combining with alkali present in moist surface tissues to form sodium sulfide, a caustic. [66] These symptoms usually subside in a few weeks.
The cells in the brain may swell to the point where blood flow is interrupted resulting in cerebral edema. Swollen brain cells may also apply pressure to the brain stem causing central nervous system dysfunction. Both cerebral edema and interference with the central nervous system are dangerous and could result in seizures, brain damage, coma ...
Mercury poisoning is a type of metal poisoning due to exposure to mercury. [3] Symptoms depend upon the type, dose, method, and duration of exposure. [3] [4] They may include muscle weakness, poor coordination, numbness in the hands and feet, skin rashes, anxiety, memory problems, trouble speaking, trouble hearing, or trouble seeing. [1]
Local pathology of neurotoxin exposure often includes neuron excitotoxicity or apoptosis [14] but can also include glial cell damage. [15] Macroscopic manifestations of neurotoxin exposure can include widespread central nervous system damage such as intellectual disability , [ 5 ] persistent memory impairments, [ 16 ] epilepsy , and dementia ...
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Lead is able to pass through the endothelial cells at the blood brain barrier because it can substitute for calcium ions and be taken up by calcium-ATPase pumps. [202] Lead poisoning interferes with the normal development of a child's brain and nervous system ; therefore children are at greater risk of lead neurotoxicity than adults are. [ 203 ]