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[7] [8] [6] It differs from the similarly named prednisone in having a hydroxyl at the 11th carbon instead of a ketone. Common side effects with short-term use include nausea, difficulty concentrating, insomnia, increased appetite, and fatigue. [5] More severe side effects include psychiatric problems, which may occur in about 5% of people. [9]
Prednisone is a synthetic glucocorticoid used for its anti-inflammatory and immunosuppressive properties. [36] [37] Prednisone is a prodrug; it is metabolised in the liver by 11-β-HSD to prednisolone, the active drug. Prednisone has no substantial biological effects until converted via hepatic metabolism to prednisolone. [38]
[28] [29] [30] Use of inhaled corticosteroids among children with asthma may result in decreased height. [ 31 ] Gastro-intestinal: While cases of colitis have been reported, corticosteroids are often prescribed when the colitis, although due to suppression of the immune response to pathogens, should be considered only after ruling out infection ...
Prednisone is the drug of choice for PMR, [19] and treatment duration is frequently greater than one year. [15] If the patient does not experience dramatic improvement after three days of 10–20 mg oral prednisone per day, the diagnosis should be reconsidered. [20] Sometimes relief of symptoms occurs in only several hours. [19]
the ratio of hip circumference to shoulder circumference varies by biological sex: the average ratio for women is 1:1.03, for men it is 1:1.18. [9] legs (floor to crotch, which are typically three-and-a-half to four heads long; arms about three heads long; hands are as long as the face. [10]
The normal subacromial space in shoulder radiographs is 9–10 mm; this space is significantly greater in men, with a slight reduction with age. [2] In middle age, a subacromial space less than 6 mm is pathological, and may indicate a rupture of the tendon of the supraspinatus muscle. [2]
These adverse sexual side effects are typically seen in less than 5% of men on the drug. There is also a link to mental health effects, including depression. However, it’s unclear how common ...
Arm span or reach (sometimes referred to as wingspan, or spelled armspan) is the physical measurement of the length from one end of an individual's arms (measured at the fingertips) to the other when raised parallel to the ground at shoulder height at a 90° angle. The arm span measurement is usually very close to the person's height.