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The wild type of this virus has a temperate life cycle that allows it to either reside within the genome of its host through lysogeny or enter into a lytic phase, during which it kills and lyses the cell to produce offspring. Lambda strains, mutated at specific sites, are unable to lysogenize cells; instead, they grow and enter the lytic cycle ...
The lytic cycle (/ ˈ l ɪ t ɪ k / LIT-ik) is one of the two cycles of viral reproduction (referring to bacterial viruses or bacteriophages), the other being the lysogenic cycle. The lytic cycle results in the destruction of the infected cell and its membrane. Bacteriophages that can only go through the lytic cycle are called virulent phages ...
At this point they initiate the reproductive cycle, resulting in lysis of the host cell. As the lysogenic cycle allows the host cell to continue to survive and reproduce, the virus is replicated in all offspring of the cell. An example of a bacteriophage known to follow the lysogenic cycle and the lytic cycle is the phage lambda of E. coli. [54]
The lytic pathway causes the host to produce and release progeny virions, usually killing it in the process. The lysogenic pathway involves the virus inserting itself into the bacterium's chromosome. At a later stage, the viral genome is activated, and it continues along the lytic pathway of producing and releasing progeny virions.
An example of a virus that uses the lysogenic cycle to its advantage is the Herpes Simplex Virus. [10] After first entering the lytic cycle and infecting a human host, it enters the lysogenic cycle. This allows it to travel to the nervous system's sensory neurons and remain undetected for long periods of time. In the case of genital herpes ...
In the lytic cycle, the virus commandeers the cell's reproductive machinery. The cell may fill with new viruses until it lyses or bursts, or it may release the new viruses one at a time in an exocytotic process. The period from infection to lysis is termed the latent period. A virus following a lytic cycle is called a virulent virus.
Temperate phages can switch between a lytic and lysogenic life cycle. Lytic is more drastic, killing the host whereas lysogenic impacts host cells genetically or physiologically. [4] [5] [6] Here is a chart on temperate phages that are lytic and lysogenic and how they're related. Lysogeny is characterized by the integration of the phage genome ...
Lambdavirus (synonyms Lambda-like viruses, Lambda-like phages, Lambda phage group, Lambda phage) is a genus of viruses in the order Caudovirales, in the family Siphoviridae. Bacteria serve as natural hosts, with transmission achieved through passive diffusion. There are five species in this genus.