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Nikolsky's sign is a clinical dermatological sign, named after Pyotr Nikolsky (1858–1940), a Russian physician who trained and worked in the Russian Empire. The sign is present when slight rubbing of the skin results in exfoliation of the outermost layer.
[2] [3] It is seen along with Nikolsky's sign, both used to assess the severity of some blistering diseases such as pemphigus vulgaris and severe bullous drug reactions. [ 4 ] This sign is named for the Danish physician Gustav Asboe-Hansen (1917–1989), who first described it in 1960.
Signs of Love is a 2022 American romantic drama film written and directed by Clarence Fuller and starring Hopper Jack Penn, Dylan Penn, Zoë Bleu and Rosanna Arquette. It is Fuller's feature directorial debut.
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SSSS is a clinical diagnosis. This is sometimes confirmed by isolation of S. aureus from blood, mucous membranes, or skin biopsy; however, these are often negative. Skin biopsy may show separation of the superficial layer of the epidermis (intraepidermal separation), differentiating SSSS from TEN, wherein the separation occurs at the dermo-epidermal junction (subepidermal separation).
Nikolsky's sign (gentle lateral pressure) on unaffected mucosa or skin raises a bulla. If no lesions are present on examination it may be useful way of demonstrating reduced epithelial adhesion. If no lesions are present on examination it may be useful way of demonstrating reduced epithelial adhesion.
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12 Signs of Love [1] (Korean: 일년에 열두남자; Hanja: 一年에 열두男子; RR: Illyeone Yeoldunamja; lit. Twelve Men in a Year) is a 2012 South Korean television series starring Yoon Jin-seo and On Joo-wan. It aired on tvN from February 15 to April 5, 2012, on Wednesdays and Thursdays at 23:00 for 16 episodes. [2]