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(1) Methamphetamine is a very dangerous and harmful drug. It is highly addictive and is associated with permanent brain damage in long-term users. (2) The abuse of methamphetamine has increased dramatically since 1990. This increased use has led to devastating effects on individuals and the community, including —
Methamphetamine is known to possess a high addiction liability (i.e., a high likelihood that long-term or high dose use will lead to compulsive drug use) and high dependence liability (i.e., a high likelihood that withdrawal symptoms will occur when methamphetamine use ceases).
Despite this, use of methamphetamine expanded from its initial base in California throughout the rural United States, especially through the Midwest and South. [16] "Government officials in a majority of U.S. counties now report that meth is their counties’ most serious drug problem.
In 2021, about 1.6 million people ages 12 and up in the U.S. had a methamphetamine use disorder and 1.4 million had a cocaine use disorder, according to data from the Substance Abuse and Mental ...
The report was the culmination of months of evidence from health and judicial experts, as well as families and communities affected by amphetamine-type substances across NSW. The report made 109 recommendations aimed to strengthen the NSW Governments response regarding amphetamine-based drugs such as crystal meth or ice.
Severe withdrawal associated with dependence from recreational substituted amphetamine use can be difficult for a user to cope with. [10] [11] [12] Long-term use of certain substituted amphetamines, particularly methamphetamine, can reduce dopamine activity in the brain. [13] [4] Adderall- Prescribed Amphetamine
An editorial article on the paper indicated that researchers had observed dopaminergic neurotoxicity (death of neurons involved in dopamine pathways) in monkeys following MDMA injections, a finding which suggested that recreational users of MDMA may be at risk of developing neuropsychiatric disorders associated with dopamine dysfunction.
Through 2009, he received research grants totaling over $6 million from the National Institute on Drug Abuse. [5] Hart's research is centered around human subject experiments conducted in his research lab at the New York State Psychiatric Institute (a hospital located in the Columbia University Irving Medical Center). The facility, informally ...