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Duloxetine, sold under the brand name Cymbalta among others, [1] is a medication used to treat major depressive disorder, generalized anxiety disorder, obsessive-compulsive disorder, fibromyalgia, neuropathic pain and central sensitization. [10] [11] It is taken by mouth. [10] Duloxetine is a serotonin–norepinephrine reuptake inhibitor (SNRI ...
Cymbalta – an ... treats nerve and muscle pain, including fibromyalgia. It can also treat seizures. M. Melatonin – a hypnotic used to treat insomnia;
SNRIs are another class of modern antidepressants. Common SNRIs include Cymbalta (duloxetine), Effexor XR (venlafaxine) and Pristiq (desvenlafaxine). Tricyclic antidepressants (TCAs). Tricyclic ...
The term "fibromyalgia" is from Neo-Latin fibro-, meaning "fibrous tissues"; Greek μυο- myo-, "muscle"; and Greek άλγος algos, "pain"; thus, the term literally means "muscle and fibrous connective tissue pain". [15] Fibromyalgia is estimated to affect 2 to 4% of the population. [16] Women are affected about twice as often as men.
The saying “knowledge is power” applies well in certain situations — like becoming a leader in your field of expertise or knowing the best places to eat (we all have different skills).
A literature review by Castagna, et. al from 2023 shows indications of efficacy treating pediatric generalized anxiety disorder. Currently, Duloxetine, an SNRI, is the only FDA-approved medication for pediatric GAD, despite the fact that SSRIs are typically first-line treatment.
Serotonin–norepinephrine reuptake inhibitors (SNRIs) such as venlafaxine (Effexor), its active metabolite desvenlafaxine (Pristiq), and duloxetine (Cymbalta) prevent the reuptake of both serotonin and norepinephrine, however their efficacy appears to be only marginally greater than the SSRIs. [218]
Duloxetine, venlafaxine, and amitriptyline are all FDA-approved for chronic musculoskeletal pain, peripheral neuropathy, and fibromyalgia). [12] [13] [14] Examples: Duloxetine; Venlafaxine; Amitriptyline