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Prasterone, also known as dehydroepiandrosterone (DHEA) and sold under the brand name Intrarosa among others, is a medication as well as over-the-counter dietary supplement which is used to correct DHEA deficiency due to adrenal insufficiency or old age, as a component of menopausal hormone therapy, to treat painful sexual intercourse due to vaginal atrophy, and to prepare the cervix for ...
7-Ketodehydroepiandrosterone (7-keto-DHEA, 7-oxo-DHEA), also known as 7-oxoprasterone, is a steroid prohormone produced by metabolism of the prohormone dehydroepiandrosterone (DHEA). [ 1 ] [ 2 ] Pharmacodynamics
Levels of DHEA-S in circulation are approximately 250 to 300 times those of DHEA. [20] DHEA-S in turn can be converted back into DHEA in peripheral tissues via steroid sulfatase (STS). [54] [55] The terminal half-life of DHEA is short at only 15 to 30 minutes. [56] In contrast, the terminal half-life of DHEA-S is far longer, at 7 to 10 hours. [56]
Older women struggling to conceive often find hope in an over-the-counter steroid hormone supplement called DHEA. Though evidence for its effectiveness is weak, DHEA has rocketed to prominence as ...
With a legacy of more than 100 years, the Better Business Bureau (BBB) is the go-to watchdog for evaluating businesses and charities. The nonprofit organization maintains a massive database of ...
Prasterone sulfate (brand names Astenile, Mylis, Teloin, others), also known as dehydroepiandrosterone sulfate (DHEA-S), is a naturally occurring androstane steroid which is marketed and used in Japan and other countries as a labor inducer in the treatment of insufficient cervical ripening and dilation during childbirth.
Dehydroepiandrosterone sulfate, abbreviated as DHEA sulfate or DHEA-S, also known as androstenolone sulfate, is an endogenous androstane steroid that is produced by the adrenal cortex. [1] It is the 3β- sulfate ester and a metabolite of dehydroepiandrosterone (DHEA) and circulates in far greater relative concentrations than DHEA. [ 2 ]
The project publishes drug reports. The first three reports covered Statins to reduce high cholesterol, heartburn drugs, and NSAIDs commonly used to treat arthritis. The project covers over 20 conditions and the most widely used drugs. [5] The reports are published in web versions and two-page PDF summaries in English and Spanish.
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