Search results
Results from the WOW.Com Content Network
Sulfadiazine is an antibiotic. [1] Used together with pyrimethamine, a dihydrofolate reductase inhibitor, it is the treatment of choice for toxoplasmosis, which is caused by a protozoan parasite. [3] It is a second-line treatment for otitis media, prophylaxis of rheumatic fever, chancroid, chlamydia, and infections by Haemophilus influenzae. [1]
Other side effects include liver inflammation, methemoglobinemia, [7] and a number of types of skin rashes. [4] While the safety of use during pregnancy is not entirely clear some physicians recommend that it be continued in those with leprosy. [4] It is of the sulfone class. [4] Dapsone was first studied as an antibiotic in 1937. [5]
Spiramycin is a macrolide antibiotic and antiparasitic. It is used to treat toxoplasmosis and various other infections of soft tissues.. Although used in Europe, Canada and Mexico, [1] spiramycin is still considered an experimental drug in the United States, but can sometimes be obtained by special permission from the FDA for toxoplasmosis in the first trimester of pregnancy. [2]
Pyrimethamine, sold under the brand name Daraprim among others, is a medication used with leucovorin (leucovorin is used to decrease side effects of pyrimethamine; it does not have intrinsic anti-parasitic activity) to treat the parasitic diseases toxoplasmosis and cystoisosporiasis.
Side effects can include gastrointestinal, esophageal or neurological issues, liver and kidney damage or allergic reactions of varying severity. Antibiotics can be crucial in treating pets. But ...
Congenital toxoplasmosis is a specific form of toxoplasmosis in which an unborn fetus is infected via the placenta. [55] Congenital toxoplasmosis is associated with fetal death and miscarriage, and in infants, it is associated with hydrocephalus, cerebral calcifications and chorioretinitis , leading to encephalopathy and possibly blindness. [ 6 ]
The effects of trimethoprim causes a backlog of dihydrofolate (DHF) and this backlog can work against the inhibitory effect the drug has on tetrahydrofolate biosynthesis. This is where the sulfamethoxazole comes in; its role is in depleting the excess DHF by preventing it from being synthesised in the first place.
For toxoplasmosis, [5] the medication has antiparasitic and therapeutic effects. For malaria, it is one of the two components (along with proguanil) in the drug Malarone. Malarone has fewer side effects and is more expensive than mefloquine. [6] Resistance has been observed. [7] For babesia, it is often used in conjunction with oral ...