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Candida auris has attracted increased clinical attention because of its multiple drug resistance. [6] [7] [4]In vitro, more than 90% of C. auris isolates are resistant to fluconazole [8] [9] and a range of 3–73% of C. auris isolates are resistant to voriconazole, [9] [10] while other triazoles (posaconazole, itraconazole, and isavuconazole) display better activity.
Candida auris is an emerging multidrug-resistant (MDR) yeast that can cause invasive infections and is associated with high mortality. It was first described in 2009 after being isolated from external ear discharge of a patient in Japan.
Invasive candidiasis is an infection (candidiasis) that can be caused by various species of Candida yeast. Unlike Candida infections of the mouth and throat (oral candidiasis) or vagina (Candidal vulvovaginitis), invasive candidiasis is a serious, progressive, and potentially fatal infection that can affect the blood (), heart, brain, eyes, bones, and other parts of the body.
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Candidiasis is a fungal infection due to any species of the genus Candida (a yeast). [4] When it affects the mouth, in some countries it is commonly called thrush. [3] Signs and symptoms include white patches on the tongue or other areas of the mouth and throat. [3]
Candida species tend to be the culprit of most fungal infections and can cause both systemic and superficial infection. [6] Th1-type cell-mediated immunity (CMI) is required for clearance of a fungal infection. Candida albicans is a kind of diploid yeast that commonly occurs among the human gut microflora. C. albicans is an opportunistic ...
Fungi that cause infections in people include yeasts, molds and fungi that are able to exist as both a mold and yeast. [3] The yeast Candida albicans can live in people without producing symptoms, and is able to cause both superficial mild candidiasis in healthy people, such as oral thrush or vaginal yeast infection , and severe systemic ...
Candida is located on most mucosal surfaces and mainly the gastrointestinal tract, along with the skin. [3] Candida albicans is one of the most commonly isolated species and can cause infections (candidiasis or thrush) in humans and other animals. In winemaking, some species of Candida can potentially spoil wines. [4]