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Typhoid fever, also known simply as typhoid, is a disease caused by Salmonella enterica serotype Typhi bacteria, also called Salmonella Typhi. [2] [3] Symptoms vary from mild to severe, and usually begin six to 30 days after exposure. [4] [5] Often there is a gradual onset of a high fever over several days. [4]
Since November 2016, Pakistan has had an outbreak of extensively drug-resistant (XDR) typhoid fever. [ 43 ] In 2020 a meta-analysis of reports of drug resistant typhoid fever revealed that among all Typhi isolates, 9,056 (25.9%) of 34,996 were resistant to chloramphenicol, 13,481 (38.8%) of 34,783 to ampicillin, and 13,366 (37.9%) of 35,270 to ...
In 1964, there was an outbreak of typhoid in the city of Aberdeen, Scotland.The first two cases were identified on 20 May 1964; eventually over 400 cases were diagnosed and the patients were quarantined at the City Hospital in Urquhart Road, Woodend Hospital in Eday Road, and Tor-na-Dee Hospital in Milltimber which was used as an overflow hospital for typhoid cases. [1]
The chlorination of public drinking water led to the sharp reduction of typhoid in developed nations. [8] In typhoid-endemic countries, Typhoid vaccines have been shown to prevent 40 to 90% of cases during the first two years, [ 9 ] and may have some effect for up to seven years.
Mary Mallon (September 23, 1869 – November 11, 1938), commonly known as Typhoid Mary, was an Irish-born American cook who is believed to have infected between 51 and 122 people with typhoid fever. The infections caused three confirmed deaths, with unconfirmed estimates of as many as 50.
The medical officer stopped keeping a record of the deaths after early October 1897 so more people may have died. The epidemic was a ‘...turning point in public health...’; during the epidemic trials of water sterilisation using chlorination and the first immunisations with typhoid vaccine were carried out in Maidstone. [3]
Just three years after the A’s drafted him out of a high school located 10 miles northeast of their home ballpark, Henderson made his major-league debut as a 20-year-old. Having already racked ...
Signs and symptoms begin with sudden onset of fever and other flu-like symptoms about one to two weeks after being infected. [10] Five to nine days after the symptoms have started, a rash typically begins on the trunk and spreads to the extremities. This rash eventually spreads over most of the body, sparing the face, palms, and soles.