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A 2018 EU-wide review of fluoroquinolones concluded that they are associated with serious side effects including tendonitis, tendon rupture, arthralgia, pain in extremities, gait disturbance, neuropathies associated with paraesthesia, depression, fatigue, memory impairment, sleep disorders, and impaired hearing, vision, taste and smell.
Prolotherapy involves the injection of an irritant solution into a joint space, [22] weakened ligament, or tendon insertion to relieve pain. [ 7 ] Most commonly, hyperosmolar dextrose (a sugar) is the solution used; [ 23 ] glycerine , [ 20 ] lidocaine (a commonly used local anesthetic ), [ 24 ] phenol , [ 20 ] and sodium morrhuate (a derivative ...
These adverse effects can involve the tendons, muscles, joints, nerves, and central nervous system." [9] Other serious side effects may include tendon rupture, tendon inflammation, seizures, psychosis, and potentially permanent peripheral nerve damage. [7] Tendon damage may appear months after treatment is completed. [7]
Cortisone’s anti-inflammatory effects can actually interfere with the body’s natural healing processes. Inflammation, while uncomfortable, is an essential part of how the body repairs itself.
Eperisone hydrochloride is available as the brand name preparations Myonal and Epry as 50 mg sugar-coated tablets, or as 10% granules for oral administration. [6] An experimental form of the drug, as a transdermal patch system, has shown promising results in laboratory tests on rodents; however, this product is not currently available for human use.
When taken by mouth, common side effects include vomiting, diarrhea, headache, and rash. [1] Other serious side effect include tendon rupture, numbness due to nerve damage, seizures, and psychosis. [1] Use in pregnancy is typically not recommended. [4] Ofloxacin is in the fluoroquinolone family of medications. [1]
Tendinopathy is a type of tendon disorder that results in pain, swelling, and impaired function. [2] The pain is typically worse with movement. [2] It most commonly occurs around the shoulder (rotator cuff tendinitis, biceps tendinitis), elbow (tennis elbow, golfer's elbow), wrist, hip, knee (jumper's knee, popliteus tendinopathy), or ankle (Achilles tendinitis).
No drug has been shown to be better than another, and all of them have adverse effects, particularly dizziness and drowsiness. [14] [16] Concerns about possible abuse and interaction with other drugs, especially if increased sedation is a risk, further limit their use. [14]
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