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Charcot's neurologic triad is the combination of nystagmus, intention tremor, and scanning or staccato speech. This triad is associated with multiple sclerosis , where it was first described; [ 1 ] however, it is not considered pathognomonic for it.
Charcot's cholangitis triad: Right Upper Quadrant Pain, Fever, Jaundice: Ascending cholangitis: Charcot's neurologic triad: scanning speech, intention tremor, nystagmus: Multiple sclerosis: Triad of congenital toxoplasmosis: chorioretinitis, hydrocephalus, intracranial calcifications: Congenital toxoplasmosis: Triad of congenital rubella
The French neurologist Jean-Martin Charcot (1825–1893) was the first person to recognize multiple sclerosis as a distinct disease in 1868. [215] Summarizing previous reports and adding his own clinical and pathological observations, Charcot called the disease sclerose en plaques .
Currently it is unknown what the primary cause of MS is; if MS is a heterogeneous disease, the lesion development process would not be unique. In particular, some PPMS patients having a special clinical course named rapidly progressive multiple sclerosis could have a special genetic cause [47] and a different development process.
infectious disease, tropical medicine heart failure Heart failure, enlarged esophagus, enlarged colon: Charcot's triad: Jean-Martin Charcot: surgery: ascending cholangitis: jaundice, fever and chills, RUQ pain Charcot's triad: Jean-Martin Charcot: neurology: multiple sclerosis: nystagmus, intention tremor, staccato speech Charcot–Leyden crystals
Multiple sclerosis is considered a disease of the white matter because normally lesions appear in this area, but it is also possible to find some of them in the grey matter. [ 30 ] Using high field MRI system, with several variants several areas show lesions, and can be spacially classified in infratentorial, callosal, juxtacortical ...
In 1868, French neurologist Jean-Martin Charcot first characterized the distinction between MS, with its resulting intention tremor, and the resting tremor characteristic of Parkinson's disease. Intention tremor became known as part of Charcot's triad [ citation needed ] (not to be confused with the Charcot triad of acute cholangitis), which ...
Unusual types of MS have been described; these include Devic's disease, Balo concentric sclerosis, Schilder's diffuse sclerosis, and Marburg multiple sclerosis. There is debate on whether they are MS variants or different diseases. [31] Multiple sclerosis behaves differently in children, taking more time to reach the progressive stage. [5]
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