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As a cough suppressant, the polistirex version lasts up to 12 hours. This duration also holds true when used recreationally. In 1981, a paper by Gosselin estimated that the lethal dose is between 50 and 500 mg/kg. Doses as high as 15–20 mg/kg are taken by some recreational users.
This page was last edited on 15 December 2024, at 21:41 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
Dextromethorphan, sold under the brand name Robitussin among others, is a cough suppressant used in many cough and cold medicines. [6] In 2022, the US Food and Drug Administration (FDA) approved the combination dextromethorphan/bupropion to serve as a rapid-acting antidepressant in people with major depressive disorder.
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[12] Codeine was once viewed as the "gold standard" in cough suppressants, but this position is now questioned. [13] Some placebo-controlled trials have found that it is ineffective against some forms of cough, including acute cough in children. [14] [15] It is thus not recommended for children.
The Prescribing Information follows one of two formats: "physician labeling rule" format or "old" (non-PLR) format. For "old" format labeling a "product title" may be listed first and may include the proprietary name (if any), the nonproprietary name, dosage form(s), and other information about the product. The other sections are as follows:
Dosage typically includes information on the number of doses, intervals between administrations, and the overall treatment period. [3] For example, a dosage might be described as "200 mg twice daily for two weeks," where 200 mg represents the individual dose, twice daily indicates the frequency, and two weeks specifies the duration of treatment.
Gutenberg Bible in the Beinecke Rare Book & Manuscript Library at Yale University in New Haven, Connecticut. The Gutenberg Bible is an edition of the Vulgate, a Latin translation of the Hebrew Bible (Old Testament) and the Greek New Testament by St Jerome. The text contains emendations from the Parisian Bible tradition, and further divergences. [5]