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In oncology, polycythemia vera (PV) is an uncommon myeloproliferative neoplasm in which the bone marrow makes too many red blood cells. [1] The majority of cases [ 2 ] are caused by mutations in the JAK2 gene, most commonly resulting in a single amino acid change in its protein product from valine to phenylalanine at position 617.
Parvalbumin (PV) is a calcium-binding protein with low molecular weight (typically 9-11 kDa). In humans, it is encoded by the PVALB gene. It is a member of the albumin family; it is named for its size ( parv- , from Latin parvus which means "small") and its ability to coagulate.
The cancer formulation of the drug, known as PV-10, is currently undergoing clinical trials for melanoma, [2] breast cancer. [ 3 ] and neuroendocrine tumors . The company also has formulated a drug based on rose bengal for the treatment of eczema and psoriasis ; this drug, PV-10, is currently in clinical trials as well.
In this particular case, it is a normal hereditary trait linked to a spotted coat color pattern and not a sign of disease. Mottle is a pattern of irregular marks, spots, streaks, blotches or patches of different shades or colours. It is commonly used to describe the surface of plants or the skin of animals.
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Burkholderia gladioli is a species of aerobic gram-negative rod-shaped bacteria [1] that causes disease in both humans and plants. It can also live in symbiosis with plants and fungi [2] and is found in soil, water, the rhizosphere, and in the microbiome of many animals.
Pigment color differs from structural color in that it is the same for all viewing angles, whereas structural color is the result of selective reflection or iridescence, usually because of multilayer structures. For example, butterfly wings typically contain structural color, although many butterflies have cells that contain pigment as well. [3]
Champagne gene, describes a different dilution gene in horses that also creates cream coloring, pale skin with mottling and light-colored eyes. Pearl gene, also called the "Barlink factor", is a recessive gene. One copy of the allele has no effect on the coat color of black, bay or chestnut horses.
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