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Sex: Women are twice as susceptible to alcohol-related liver disease, and may develop alcoholic liver disease with shorter durations and doses of chronic consumption. The lesser amount of alcohol dehydrogenase secreted in the gut, higher proportion of body fat in women, and changes in alcohol absorption due to the menstrual cycle may explain ...
Alcohol appears to trigger the secretion of pro-inflammatory cytokines, elevating inflammation and promoting liver damage. Regular drinking can also lead to alcoholic fatty liver disease—a build ...
“Over time, this repeated damage can result in cirrhosis, where the liver becomes so scarred that it loses functionality,” she explains. This may eventually raise the risk of liver cancer. 2.
Risks include alcohol use disorder, malnutrition, chronic pancreatitis, alcoholic liver disease (e.g., permanent liver scarring) and several types of cancer. In addition, damage to the central nervous system and peripheral nervous system (e.g., painful peripheral neuropathy) can occur from chronic alcohol misuse. [46] [47]
The level of ethanol consumption that minimizes the risk of disease, injury, and death is subject to some controversy. [16] Several studies have found a J-shaped relationship between alcohol consumption and health, [17] [18] [2] [19] meaning that risk is minimized at a certain (non-zero) consumption level, and drinking below or above this level increases risk, with the risk level of drinking a ...
In a 2023 study published in the journal Alcohol, chronic heavy alcohol consumption was found to cause DNA damage and oxidative stress, which can lead to an increased risk of cancer ...
Additionally, drinking alcohol can put a dent in a person's nutrition, preventing the body from absorbing folic acid, which is critical to all our cells. It can also block the uptake of important ...
High consumption of alcohol can lead to several forms of liver disease including alcoholic hepatitis, alcoholic fatty liver disease, cirrhosis, and liver cancer. [42] In the earlier stages of alcoholic liver disease, fat builds up in the liver's cells due to increased creation of triglycerides and fatty acids and a decreased ability to break ...