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Ketamine-assisted psychotherapy (KAP) is the use of prescribed doses of ketamine as an adjunct to psychotherapy sessions. KAP shows significant potential in treating mental disorders such as treatment-resistant depression (TRD), anxiety , obsessive–compulsive disorders (OCD), post-traumatic stress disorders (PTSD), and other conditions. [ 1 ]
Ketamine has sedative, analgesic, and amnestic properties, but most of its uses today are focused on analgesia. Some of the benefits of ketamine is that it does not compromise the patient's airway protective reflexes, keeps the upper airway muscle tone, and allows for spontaneous breathing. A common side effect of ketamine is emergence reactions.
It is also used as a treatment for depression and in pain management. [19] Ketamine is an NMDA receptor antagonist which accounts for most of its psychoactive effects. [20] At anesthetic doses, ketamine induces a state of dissociative anesthesia, a trance-like state providing pain relief, sedation, and amnesia. [21]
NMDA receptor antagonists induce a state called dissociative anesthesia, marked by catalepsy, amnesia, and analgesia. [1] Ketamine is a favored anesthetic for emergency patients with unknown medical history and in the treatment of burn victims because it depresses breathing and circulation less than other anesthetics.
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The most common standard conscious sedation technique for adults is intravenous sedation using Midazolam. This requires a needle to be put into a vein to deliver the medication; this is known as an IV cannula. [citation needed] Indications: [citation needed] Reduced dental anxiety and phobia; Traumatic or prolonged dental procedures
The doses for intravenous sedative-hypnotic and adjuvant agents vary individually. Pharmacodynamic and pharmacokinetic factors need to be considered for each patient (e.g. patients with impaired kidney or liver function, blood abnormalities and myocardial dysfunction , etc.) [ 16 ] There are also risks of adverse effects related to doses such ...
The finding by the Los Angeles County medical examiner that "Friends" star Matthew Perry died from "acute effects" of ketamine is generating interest in the drug.. Ketamine is generally safe when ...