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The specialist Immunohematology and Transfusion Physician provides expert opinion for difficult transfusions, massive transfusions, incompatibility work up, therapeutic plasmapheresis, cellular therapy, irradiated blood therapy, leukoreduced and washed blood products, stem cell procedures, platelet rich plasma therapies, HLA and cord blood ...
Platelet transfusions came into medical use in the 1950s and 1960s. [1] [5] It is on the World Health Organization's List of Essential Medicines. [6] [7] Some versions of platelets have had the white blood cells partially removed or been gamma irradiated which have specific benefits for certain populations. [8]
However, it is important that a full medical history be elicited to ensure that the increased platelet count is not due to a secondary process. Often, it occurs in tandem with an inflammatory disease as the principal stimulants of platelet production (e.g. thrombopoietin ) are elevated in these clinical states as part of the acute phase reaction .
The International Bible Society (now known as Biblica) published the New Testament of the New Urdu Bible Version (NUBV) in 2009. This is based on their 1983 revision of New International Version (NIV) in English. [19] It was published in India only, not in Pakistan. In 2011 the Urdu Geo Version was published by Geolink Resources LLC.
Packed red blood cells, fresh frozen plasma, and platelets are generally administered. [131] Typical ratios of fresh frozen plasma, platelets and packed red blood cells are between 1:1:1 and 1:1:2. [132] In some locations, blood has begun to be administered pre-hospital in an effort to reduce preventable deaths from significant blood loss.
The blood donor center is the facility that collects blood components from screened blood donors, either whole blood or separate components such as plasma or platelets only via apheresis. These blood components are then transported to a central location for processing such as fractionation, testing and redistribution.
Irradiation is the process by which an object is exposed to radiation. An irradiator is a device used to expose an object to radiation, notably gamma radiation , for a variety of purposes. [ 1 ]
One common definition of thrombocytopenia requiring emergency treatment is a platelet count below 50,000/μL. [5] Thrombocytopenia can be contrasted with the conditions associated with an abnormally high level of platelets in the blood – thrombocythemia (when the cause is unknown), and thrombocytosis (when the cause is known). [6] [7]