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A mix-up rated as contamination could in reality be a simple confusion of two cell lines, but usually contamination is assumed. [ citation needed ] After a cell line has been discovered to be contaminated, it is usually never used again for research demanding the specific type of cell line they were assumed to be.
Bioburden is normally defined as the number of bacteria living on a surface that has not been sterilized. [1]The term is most often used in the context of bioburden testing, also known as microbial limit testing, which is performed on pharmaceutical products and medical products for quality control purposes.
For curative treatments or rapidly changing conditions, cross-over trials may be infeasible or unethical. Crossover studies often have two problems: First is the issue of "order" effects, because it is possible that the order in which treatments are administered may affect the outcome. An example might be a drug with many adverse effects given ...
A cohort study is a particular form of longitudinal study that samples a cohort (a group of people who share a defining characteristic, typically those who experienced a common event in a selected period, such as birth or graduation), performing a cross-section at intervals through time.
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Interplanetary contamination refers to biological contamination of a planetary body by a space probe or spacecraft, either deliberate or unintentional. There are two types of interplanetary contamination: Forward contamination is the transfer of life and other forms of contamination from Earth to another celestial body.
Cross-resistance can take place between compounds that are chemically similar, like antibiotics within similar and different classes. [9] That said, structural similarity is a weak predictor of antibiotic resistance, and does not predict antibiotic resistance at all when aminoglycosides are disregarded in the comparison.
Microbial corrosion, also known as microbiologically influenced corrosion (MIC), microbially induced corrosion (MIC) or biocorrosion, occurs when microbes affect the electrochemical environment of the surface on which they are fixed.