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Serious side effects may include abuse, but do not include pulmonary hypertension or valvular heart disease, as the latter complications were caused by the fenfluramine component of the "fen-phen" combination. [3] Phentermine is an norepinephrine and dopamine releasing agent (NDRA) and produces stimulant, rewarding, and appetite suppressant ...
Adverse effects were less frequent with the combination regimen than with the other active (non-placebo) treatments. The authors felt that combining fenfluramine and phentermine capitalized on their pharmacodynamic differences, resulting in equivalent weight loss, fewer adverse effects, and better appetite control. [4]
Side Effects and Risks of Weight Loss Injections Even though GLP-1s and GIP/GLP-1s are safe for most people, there are some side effects to keep in mind. The most common side effects are ...
Common side effects include tingling, dizziness, trouble sleeping, and constipation. [3] Serious side effects may include suicide, abuse. [3] Use is not recommended during pregnancy. [1] Phentermine is a stimulant and appetite suppressant. [3] Topiramate is an anticonvulsant that has weight loss side effects. [3]
Its sympathomimetic effects are mediated by indirect activation of α-and β-adrenergic receptors. [5] Chemically, it is a substituted phenethylamine and amphetamine and is closely related to phentermine and methamphetamine. [4] [9] [1] Mephentermine was first described and introduced for medical use by 1952. [10]
Fenfluramine is indicated for the treatment of seizures associated with Dravet syndrome and Lennox–Gastaut syndrome in people age two and older. [3] [7] [4]Dravet syndrome is a life-threatening, rare and chronic form of epilepsy. [7]
Hepatotoxicity, dermatological side effects, and abuse potential. [7] Aminopyrine: 1999 France, Thailand Risk of agranulocytosis and severe acne. [3] Amobarbital: 1980 Norway Risk of barbiturate toxicity. [3] Amoproxan: 1970 France Dermatologic and ophthalmic toxicity. [3] Anagestone acetate: 1969 Germany Animal carcinogenicity. [3] Antrafenine ...
Chlorphentermine, sold under the brand names Apsedon, Desopimon, and Lucofen, is a serotonergic appetite suppressant of the amphetamine family. Developed in 1962, it is the para-chloro derivative of the better-known appetite suppressant phentermine, which is still in current use.