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Graft-versus-host disease is an autoimmune condition that occurs as a result of bone-marrow transplants in which the immune cells from the transplanted bone marrow attack the host's body. Mycosis fungoides is a type of cutaneous T cell lymphoma , a rare cancer that causes rashes all over the body.
Sclerosis (from Ancient Greek σκληρός (sklērós) 'hard') is the stiffening of a tissue or anatomical feature, usually caused by a replacement of the normal organ-specific tissue with connective tissue. The structure may be said to have undergone sclerotic changes or display sclerotic lesions, which refers to the process of sclerosis.
Instead, the drugs affect new blood cells that are being made by the bone marrow. [4] When myelosuppression is severe, it is called myeloablation. [5] Many other drugs including common antibiotics may cause bone marrow suppression. Unlike chemotherapy the effects may not be due to direct destruction of stem cells but the results may be equally ...
[8] [9] They referred to the plaques as 'nodules of neuroglial sclerosis'. In 1898, Emil Redlich reported plaques in three patients, two of whom had clinically verified dementia. [10] Redlich used the term 'miliary sclerosis' to describe plaques because he thought they resembled millet seeds, and he was the first to refer to the lesions as ...
The sclerosis typically affects one side of the cortex of the involved bone, appearing similar to wax melting down one side of a candle. [1] Melorheostosis most commonly affects the long bones of the upper and lower extremities, but can also be seen in the hands and feet. [2] It is usually an incidental finding and most patients are ...
Sclerosteosis is an autosomal recessive disorder characterized by bone overgrowth. It was first described in 1958 [1] [2] but given the current name in 1967. [3] Excessive bone formation is most prominent in the skull, mandible and tubular bones. [1] It can cause facial distortion and syndactyly. [1]
Erythropoetin, a hormone made by the kidneys, controls the production of red blood cells as well as the rate at which they are released from the bone marrow. When these levels of erythropoetin rise, they signal the release of immature red blood cells into the bloodstream and is linked to anemia. Damaged bone marrow can also lead to polychromasia.
Clinical appearance of acrosclerotic piece-meal necrosis of the thumb in a patient with systemic sclerosis. Systemic scleroderma in the limbs, showing carcinoma subsequent to ulceration. In the skin, systemic sclerosis causes hardening and scarring. The skin may appear tight, reddish, or scaly. Blood vessels may also be more visible.