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Death is often due to lung, gastrointestinal, or heart complications. [3] About three per 100,000 people per year develop the systemic form. [3] The condition most often begins in middle age. [1] Women are more often affected than men. [1] Scleroderma symptoms were first described in 1753 by Carlo Curzio [9] and then well documented in 1842. [10]
Osteosclerosis is a disorder characterized by abnormal hardening of bone and an elevation in bone density. It may predominantly affect the medullary portion and/or cortex of bone. Plain radiographs are a valuable tool for detecting and classifying osteosclerotic disorders. [1] [2] It can manifest in localized or generalized osteosclerosis.
Sclerosteosis is an autosomal recessive disorder characterized by bone overgrowth. It was first described in 1958 [1] [2] but given the current name in 1967. [3] Excessive bone formation is most prominent in the skull, mandible and tubular bones. [1] It can cause facial distortion and syndactyly. [1]
Sclerosis (from Ancient Greek σκληρός (sklērós) 'hard') is the stiffening of a tissue or anatomical feature, usually caused by a replacement of the normal organ-specific tissue with connective tissue. The structure may be said to have undergone sclerotic changes or display sclerotic lesions, which refers to the process of sclerosis.
Binswanger's disease is a type of subcortical vascular dementia caused by white matter atrophy to the brain. However, white matter atrophy alone is not sufficient for this disease; evidence of subcortical dementia is also necessary.
[8] [9] They referred to the plaques as 'nodules of neuroglial sclerosis'. In 1898, Emil Redlich reported plaques in three patients, two of whom had clinically verified dementia. [10] Redlich used the term 'miliary sclerosis' to describe plaques because he thought they resembled millet seeds, and he was the first to refer to the lesions as ...
Meditation may also help reduce the risk of dementia because it can reduce high blood pressure and anxiety, both risk factors for Alzheimer's disease and other types of dementia, research shows ...
Clinical appearance of acrosclerotic piece-meal necrosis of the thumb in a patient with systemic sclerosis. Systemic scleroderma in the limbs, showing carcinoma subsequent to ulceration. In the skin, systemic sclerosis causes hardening and scarring. The skin may appear tight, reddish, or scaly. Blood vessels may also be more visible.
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