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Whereas acute leukemia must be treated immediately, chronic forms are sometimes monitored for some time before treatment to ensure maximum effectiveness of therapy. Chronic leukemia mostly occurs in older people but can occur in any age group. Additionally, the diseases are subdivided according to which kind of blood cell is affected.
This disease most commonly affects individuals over the age of 65, due to the accumulation of genetic mutations that occur over time. [3] [20] CLL is rarely seen in individuals less than 40 years old. [19] Men are more commonly affected than women, although the average lifetime risk for both genders are similar (around 0.5-1%) .
This declines with age, with the poorer prognosis being associated with an age greater than 65 years, and the poorest prognosis seen in those aged 75–84. [ 11 ] As of 2001, cure rates in clinical trials have ranged from 20 to 45%; [ 75 ] [ 76 ] although clinical trials often include only younger people and those able to tolerate aggressive ...
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Leukemia is the most common cancer in children, accounting for 25-30% of all cancers in children and adolescents. [1] [29] [27] It most commonly is diagnosed in children when they are 1–4 years old. The median age of diagnosis is 6 years old. Childhood leukemia is more common in boys than girls.
T-cell-prolymphocytic leukemia (T-PLL) is a mature T-cell leukemia with aggressive behavior and predilection for blood, bone marrow, lymph nodes, liver, spleen, and skin involvement. [1] T-PLL is a very rare leukemia, primarily affecting adults over the age of 30. It represents 2% of all small lymphocytic leukemias in adults. [2]
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