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It is most commonly used in dental procedures to numb the area around a tooth [1] and is also used to reduce the pain of intramuscular injection of penicillin. Owing to the ubiquity of the trade name Novocain or Novocaine, in some regions, procaine is referred to generically as novocaine. It acts mainly as a sodium channel blocker. [2]
Intraligamentary or periodontal ligament anaesthesia is a technique used primarily for endodontic treatment and to supplement inferior dental blocks where they may have failed. This technique involves 'the deposition of at least 0.2ml of local anaesthetic solution for each root of the tooth' [ 10 ] diffusing into the marrow spaces surrounding ...
Novocain, borocaine (procaine borate), ethocaine 1904 (Alfred Einhorn) 1905 (Heinrich Braun) procainamide: proparacaine: proxymetacaine propoxycaine [16] Pyrrocaine [17] quinisocaine dimethisoquin [18] ropivacaine: Naropin 1957 (Ekenstam) 1997 trimecaine: Mesdicain, Mesocain, Mesokain tetracaine: amethocaine, Dicaine, Pontocaine 1928 (O. Eisleb ...
Inferior alveolar nerve block (abbreviated to IANB, and also termed inferior alveolar nerve anesthesia or inferior dental block) is a nerve block technique which induces anesthesia (numbness) in the areas of the mouth and face innervated by one of the inferior alveolar nerves which are paired on the left and right side.
A topical anesthetic is a local anesthetic that is used to numb the surface of a body part. They can be used to numb any area of the skin as well as the front of the eyeball, the inside of the nose, ear or throat, the anus and the genital area. [1]
Articaine is a dental amide-type local anesthetic. It is the most widely used local anesthetic in a number of European countries [ 2 ] and is available in many countries. It is the only local anaesthetic to contain a thiophene ring , meaning it can be described as 'thiophenic'; this conveys lipid solubility.
Fetal pH is slightly lower than maternal (7.32 to 7.38), thus most unionized drugs are "ion trapped" to a degree, even in a healthy fetus. Chloroprocaine (pKa 8.7) is the drug of choice for epidural analgesia and a decompensating fetus, because it does not participate in ion trapping. Placental transfer of 2-chloroprocaine is not influenced by ...
Two Dental Corps officers were killed and four were wounded in the attack on Pearl Harbor in 1941; they would not be the last dental officers to die in the line of duty. As the US got ready for world conflict, Navy Dentistry's active duty numbers swelled to its highest levels ever – ultimately reaching 7,000 dental officers and 11,000 dental ...