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  2. Aromatase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Aromatase_inhibitor

    Aromatase inhibitors (AIs) are a class of drugs used in the treatment of breast cancer in postmenopausal women and in men, [1] [2] and gynecomastia in men. They may also be used off-label to reduce estrogen conversion when supplementing testosterone exogenously. They may also be used for chemoprevention in women at high risk for breast cancer.

  3. Estrogen deprivation therapy - Wikipedia

    en.wikipedia.org/wiki/Estrogen_deprivation_therapy

    Estrogen deprivation therapy, also known as endocrine therapy, is a form of hormone therapy that is used in the treatment of breast cancer.Modalities include antiestrogens or estrogen blockers such as selective estrogen receptor modulators (SERMs) like tamoxifen, selective estrogen receptor degraders like fulvestrant, and aromatase inhibitors like anastrozole and ovariectomy.

  4. Antiestrogen - Wikipedia

    en.wikipedia.org/wiki/Antiestrogen

    Antiestrogens, also known as estrogen antagonists or estrogen blockers, are a class of drugs which prevent estrogens like estradiol from mediating their biological effects in the body. They act by blocking the estrogen receptor (ER) and/or inhibiting or suppressing estrogen production .

  5. Breast cancer management - Wikipedia

    en.wikipedia.org/wiki/Breast_cancer_management

    Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.

  6. Steroidal aromatase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Steroidal_aromatase_inhibitor

    Steroidal aromatase inhibitors are a class of drugs that are mostly used for treating breast cancer in postmenopausal women. High levels of estrogen in breast tissue increases the risk of developing breast cancer and the enzyme aromatase is considered to be a good therapeutic target when treating breast cancer due to it being involved in the final step of estrogen biosynthetic pathway and also ...

  7. Hormonal therapy (oncology) - Wikipedia

    en.wikipedia.org/wiki/Hormonal_therapy_(oncology)

    Tamoxifen is currently first-line treatment for nearly all pre-menopausal women with hormone receptor-positive breast cancer. [1] Raloxifene is another partial agonist SERM which does not seem to promote endometrial cancer , and is used primarily for chemoprevention of breast cancer in high-risk individuals, as well as to prevent osteoporosis ...

  8. 'Why I Returned To Bodybuilding At 75 After A Breast Cancer ...

    www.aol.com/lifestyle/why-returned-bodybuilding...

    Here's how her fitness routine helped her face her fears following a cancer diagnosis and return to bodybuilding. ... After I was diagnosed with breast cancer in 2023, my world was turned upside ...

  9. Drostanolone propionate - Wikipedia

    en.wikipedia.org/wiki/Drostanolone_propionate

    Some types of breast cancer cells, expressing estrogen receptors (called ER+ cancers), use estrogen for their growth and dissemination. That is why drugs that block estrogen receptors or decrease their expression on the cell membrane, antiestrogens, could limit the tumor spread and size. Drostanolone propionate has been FDA approved [7] as an ...

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