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Initially, manual slicing of tissues, such as the liver, led to significant variability in thickness and limited viability. [5] A critical advancement occurred in the 1940s when Stadie and Riggs introduced a microtome equipped with a thin razor blade, reducing thickness variability to about 5%. These improved slices became known as precision ...
In addition, interference microscopy of the cut surface of the blocks reveals that the sections are often not flat. With Epon or Vestopal as embedding medium the ridges and valleys usually do not exceed 0.5 μm in height, i.e., 5–10 times the thickness of ordinary sections (1). A small sample is taken from the specimen to be investigated.
Low-dose high-resolution (1.25 mm) chest CT. HRCT is performed using a conventional CT scanner. However, imaging parameters are chosen so as to maximize spatial resolution: [1] a narrow slice width is used (usually 1–2 mm), a high spatial resolution image reconstruction algorithm is used, field of view is minimized, so as to minimize the size of each pixel, and other scan factors (e.g. focal ...
Medical ultrasound includes diagnostic techniques (mainly imaging techniques) using ultrasound, as well as therapeutic applications of ultrasound. In diagnosis, it is used to create an image of internal body structures such as tendons, muscles, joints, blood vessels, and internal organs, to measure some characteristics (e.g., distances and velocities) or to generate an informative audible sound.
Ultrasound-modulated optical tomography: Ultrasound: UOT Ultrasound computer tomography: Ultrasound: USCT Ultrasound transmission tomography: Ultrasound: X-ray computed tomography: X-ray: CT, CAT scan 1971 X-ray microtomography [15] X-ray: microCT Zeeman-Doppler imaging: Zeeman effect
Synthetic aperture ultrasound (SAU) imaging is an advanced form of imaging technology used to form high-resolution images in biomedical ultrasound systems. Ultrasound imaging has become an important and popular medical imaging method, as it is safer and more economical than computer tomography (CT) and magnetic resonance imaging (MRI).
The slice preparation procedure itself induces a rapid and robust phenotype change in microglia, the consequences of which need to be taken into consideration when interpreting results. [ 4 ] During recording, the tissue also "ages", degrading at a faster rate than in the intact animal.
By changing the pulse delays, the computer can scan the beam of ultrasound in a raster pattern across the tissue. Echoes reflected by different density tissue, received by the transducers, build up an image of the underlying structures. Weld examination by phased array. TOP: The phased array probe emits a series of beams to flood the weld with ...