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Baclofen, diazepam and dantrolene remain the three most commonly used pharmacologic agents in the treatment of spastic hypertonia. Baclofen is generally the drug of choice for spinal cord types of spasticity, while sodium dantrolene is the only agent which acts directly on muscle tissue. Tizanidine is also available.
The Bobath concept is an approach to neurological rehabilitation that is applied in patient assessment and treatment (such as with adults after stroke [1] or children with cerebral palsy [2]). The goal of applying the Bobath concept is to promote motor learning for efficient motor control in various environments, thereby improving participation ...
Treatment of spastic gait may include physiotherapy, drugs that relax the muscles (including baclofen and tizanidine), and local botulinum toxin injections. [1] [2]
Spasticity mostly occurs in disorders of the central nervous system (CNS) affecting the upper motor neurons in the form of a lesion, such as spastic diplegia, or upper motor neuron syndrome, and can also be present in various types of multiple sclerosis, where it occurs as a symptom of the progressively-worsening attacks on myelin sheaths and ...
Medicinal – Medication targeting symptoms associated with spasticity is also a relatively new treatment that is utilized but is still in the early stages of development. Drugs such as baclofen, benzodiazepines (e.g., diazepam), tizanidine, and sometimes dantrolene have shown promise in the effort to diminish spasticity. [ 10 ]
Treatment is focused on improving sensation and motor abilities, allowing the patient to better manage their activities of daily living. Some strategies used for treatment include promoting the use of the hemiparetic limb during functional tasks, maintaining range of motion, and using neuromuscular electrical stimulation to decrease spasticity ...
This can include conditions such as spinal cord injury, brain injury, musculoskeletal injury, stroke, pain and spasticity from muscle, ligament, or nerve damage. PM&R physicians lead rehabilitation teams and are trained in medication management, electrodiagnosis, and targeted injections. [2]
Botulinum toxin is focal treatment, meaning that a limited number of muscles can be injected at the same time. The effect of the toxin is reversible and a reinjection may be needed every 4–6 months. [61] In children it decreases spasticity and improve range of motion and thus has become commonly used.
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