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Lamotrigine is metabolized predominantly by glucuronic acid conjugation. Its major metabolite is an inactive 2-n-glucuronide conjugate. [82] Lamotrigine has fewer drug interactions than many anticonvulsant drugs, although pharmacokinetic interactions with carbamazepine, phenytoin and other hepatic enzyme-inducing medications may shorten half ...
Lamotrigine: Lamictal Levetiracetam: Keppra Lithium salts: Camcolit, Eskalith, Lithobid, Sedalit Oxcarbazepine: Trileptal Topiramate: Topamax Sodium valproate [note 1] Convulex, Depakene, Depakine Enteric, Orfiril, Stavzor Divalproex sodium [note 2] Depakote, Epival, Ergenyl Chrono Sodium valproate and valproic acid in 2.3:1 ratio
Lamictal (lamotrigine) – an anticonvulsant used as a mood stabilizer; Latuda – an atypical antipsychotic; Lexapro (escitalopram) – an antidepressant of the SSRI class; Librium (chlordiazepoxide) – a benzodiazepine used to treat acute alcohol withdrawal; Lithobid, Eskalith – a mood stabilizer
Viatris Inc. is an American global pharmaceutical and healthcare corporation headquartered in Canonsburg, Pennsylvania.The corporation was formed through the merger of Mylan and Upjohn, a legacy division of Pfizer, on November 16, 2020.
PILLS (Patient Information Language Localisation System) is a one-year effort by the European Commission to produce a prototype tool which will support the creation of various kinds of medical documentation simultaneously in multiple languages, by storing the information in a database and allowing a variety of forms and languages of output.
The ketogenic diet consists of a high-fat, low-carbohydrate diet, and has shown good results in patients whose epilepsy has not responded to medications and who cannot receive surgery. The vagus nerve stimulator is a device that can be implanted into patients with epilepsy, especially that which originates from a specific part of the brain ...
Patients typically present to medical providers following their first generalized tonic–clonic seizure, by which time they have often had myoclonus for several years. The first generalized tonic–clonic seizure usually occurs in the context of a particular provoking factor, such as sleep deprivation, stress or alcohol consumption. [ 15 ]
In juvenile myoclonic epilepsy, it is a second-line therapy, reserved for when the valproates or lamotrigine do not work and when the other second-line therapy, acetazolamide, does not work. [14] The usual dose for seizure disorder is titrated from 100-125 mg/day up to a maintenance dose of 750-1,500 mg/day (maximum daily dosage is 2 g).
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