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A patch test relies on the principle of a type IV hypersensitivity reaction.. The first step in becoming allergic is sensitization. When skin is exposed to an allergen, the antigen-presenting cells (APCs) – also known as Langerhans cell or Dermal Dendritic Cell – phagocytize the substance, break it down to smaller components and present them on their surface bound major histocompatibility ...
A patch test (contact delayed hypersensitivity allergy test) [17] is a commonly used examination to determine the exact cause of an allergic contact dermatitis. According to the American Academy of Allergy, Asthma, and Immunology, "patch testing is the gold standard for contact allergen identification".
The Schick test, developed in 1913, [1] is a skin test used to determine whether or not a person is susceptible to diphtheria. [2] It was named after its inventor, Béla Schick (1877–1967), a Hungarian-born American pediatrician.
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For metal allergens, patch test reproducibility is low, and the extent to which they predict implant failures is debated. If the person being tested has a rash already, it may be difficult to do a patch test. Patch testing may also worsen the allergy. it is also difficult to distinguish co-sensitivity from cross-sensitivity using a patch test.
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Print/export Download as PDF; Printable version; In other projects Wikidata item; ... 56 Patch testing may be used to diagnose the cause. [2]
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