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Skeletal formula of the antibiotic linezolid, highlighting the oxazolidinone pharmacophore (in blue) and desirable structural characteristics (in orange). Created using ACD/ChemSketch 10.0 and Inkscape. Date: 24 June 2009: Source: Own work based on: Brickner SJ (1996).
Linezolid is a member of the oxazolidinone class of medications. [10] Linezolid was discovered in the mid-1990s, and was approved for commercial use in 2000. [16] [17] It is on the World Health Organization's List of Essential Medicines. [18] The World Health Organization classifies linezolid as critically important for human medicine. [19]
The main pathways of linezolid metabolism in humans, showing all metabolites that account for >1% of an excreted dose. Legend. PNU-142300, accounts for ~10% of excreted dose at steady state; PNU-142586, accounts for ~45% of excreted dose at steady state; PNU-173558, accounts for ~3.3% of excreted dose at steady state; Date: 15 May 2009: Source
The following other wikis use this file: Usage on ar.wikipedia.org لينيزوليد; Usage on azb.wikipedia.org لینزولید; Usage on cy.wikipedia.org
In other cases, topical is defined as applied to a localized area of the body or to the surface of a body part regardless of the location of the effect. [4] [5] By this definition, topical administration also includes transdermal application, where the substance is administered onto the skin but is absorbed into the body to attain systemic ...
The human body consists of biological systems, that consist of organs, that consist of tissues, that consist of cells and connective tissue. The history of anatomy has been characterized, over a long period of time, by a continually developing understanding of the functions of organs and structures in the body.
The clitoris is the only organ in the human body that exists exclusively for pleasure. Those in the medical community had no reason to assume they were wrong. The anatomical “maps” that anchored their education must have seemed as sturdy and steadfast as Mercator’s, with every organ plotted and every muscle annotated.
First-pass metabolism may occur in the liver (for propranolol, lidocaine, clomethiazole, and nitroglycerin) or in the gut (for benzylpenicillin and insulin). [4] The four primary systems that affect the first pass effect of a drug are the enzymes of the gastrointestinal lumen, [5] gastrointestinal wall enzymes, [6] [7] [8] bacterial enzymes [5] and hepatic enzymes.