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  2. Clark's rule - Wikipedia

    en.wikipedia.org/wiki/Clark's_rule

    Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK, the West Indies ...

  3. Amoxicillin/clavulanic acid - Wikipedia

    en.wikipedia.org/wiki/Amoxicillin/clavulanic_acid

    However, across the spectrum of dosage of amoxicillin-clavulanate combination, the dose of clavulanate is constant at 125 mg, whereas the dose of amoxicillin varies at 250 mg, 500 mg and 875 mg. Thus the use of low-dose amoxicillin-clavulanate in combination with meropenem may be used in part of a treatment regimen for drug-resistant TB and ...

  4. Broselow tape - Wikipedia

    en.wikipedia.org/wiki/Broselow_tape

    The Broselow Tape relates a child's height as measured by the tape to their weight to provide medical instructions including medication dosages, the size of the equipment that should be used, and the level of energy when using a defibrillator. Particular to children is the need to calculate all these therapies for each child individually.

  5. Management of tuberculosis - Wikipedia

    en.wikipedia.org/wiki/Management_of_tuberculosis

    Day 2: INH at 1/2 dose; Day 3: INH at full dose; Day 4: RMP at 1/3 or 1/4 dose; Day 5: RMP at 1/2 dose; Day 6: RMP at full dose; Day 7: EMB at 1/3 or 1/4 dose; Day 8: EMB at 1/2 dose; Day 9: EMB at full dose; No more than one test dose per day should be given, and all other drugs should be stopped while test dosing is being done. So on day 4 ...

  6. Clavulanic acid - Wikipedia

    en.wikipedia.org/wiki/Clavulanic_acid

    [4] [19] [24] However, development for these indications was discontinued by 2014. [4] The developmental code name of clavulanic acid was RX-10100 and its tentative brand names were Serdaxin and Zoraxel. [4] Although its development was discontinued, interest in clavulanic acid for potential nervous system-related uses has continued as of 2024 ...

  7. Area under the curve (pharmacokinetics) - Wikipedia

    en.wikipedia.org/wiki/Area_under_the_curve...

    Absolute bioavailability refers to the bioavailability of a drug when administered via an extravascular dosage form (i.e. oral tablet, suppository, subcutaneous, etc.) compared with the bioavailability of the same drug administered intravenously (IV). This is done by comparing the AUC of the non-intravenous dosage form with the AUC for the drug ...

  8. Amoxicillin - Wikipedia

    en.wikipedia.org/wiki/Amoxicillin

    Amoxicillin was discovered in 1958 and came into medical use in 1972. [12] [13] Amoxil was approved for medical use in the United States in 1974, [4] [5] and in the United Kingdom in 1977. [2] It is on the World Health Organization's List of Essential Medicines. [14] It is one of the most commonly prescribed antibiotics in children. [15]

  9. Defined daily dose - Wikipedia

    en.wikipedia.org/wiki/Defined_Daily_Dose

    The dose is based on recommendations for treatment rather than prevention, except if prevention is the main indication. Generally there is only one DDD for all formulations of a drug, however exceptions are made if some formulations are typically used in significantly different strengths (e.g., antibiotic injection in a hospital vs tablets in ...