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Phineas P. Gage (1823–1860) was an American railroad construction foreman remembered for his improbable: 19 survival of an accident in which a large iron rod was driven completely through his head, destroying much of his brain's left frontal lobe, and for that injury's reported effects on his personality and behavior over the remaining 12 years of his life—effects sufficiently ...
White matter fiber connections in DTI data are then drawn between these cortical regions and weighted by fractional anisotropy and strength of the connection. Such graphs have even been used to analyze the damage done to the famous traumatic brain injury patient Phineas Gage. [56]
The uncinate fasciculus is a white matter association tract in the human brain that connects parts of the limbic system such as the temporal pole, anterior parahippocampus, and amygdala in the temporal lobe with inferior portions of the frontal lobe such as the orbitofrontal cortex.
Phineas Gage got an iron rod shot up through his skull, injuring his brain and his skull and blinding him in his left eye. His surgeon performed medical surgery on him that relieved the pressure in his skull which ultimately saved his life (King Henri II, if he had received a similar procedure, may have survived).
Phineas Gage Skull of Phineas Gage. The Warren Anatomical Museum, housed within Harvard Medical School's Countway Library of Medicine, was founded in 1847 by Harvard professor John Collins Warren, [1] whose personal collection of 160 [2] unusual and instructive anatomical and pathological specimens now forms the nucleus of the museum's 15,000-item collection. [3]
White matter is the tissue through which messages pass between different areas of grey matter within the central nervous system. The white matter is white because of the fatty substance (myelin) that surrounds the nerve fibers (axons). This myelin is found in almost all long nerve fibers, and acts as an electrical insulation.
The connectogram, as a graphical representation of brain connectomics, was proposed in 2012. [1]Circular representations of connections have been used in a number of disciplines; examples include representation of aspects of epidemics, [2] geographical networks, [3] musical beats, [4] diversity in bird populations, [5] and genomic data. [6]
While working on the Rutland & Burlington railroad in Cavendish, Vermont, with his former physics teacher Hosea Doton, [3] he was the first physician to treat railroad contractor Phineas Gage after Gage survived accidentally blasting a tamping iron through his jaw and skull while setting an explosive charge. [4]