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  2. Retinitis pigmentosa - Wikipedia

    en.wikipedia.org/wiki/Retinitis_pigmentosa

    Retinitis pigmentosa (RP) is a member of a group of genetic disorders called inherited retinal dystrophy (IRD) that cause loss of vision. [1] Symptoms include trouble seeing at night and decreasing peripheral vision (side and upper or lower visual field). [1]

  3. Phene - Wikipedia

    en.wikipedia.org/wiki/Phene

    On the contrary the results of these studies implicate a large number of gene alleles that have a very small effect (phene). [ 2 ] It is important to note that the word phenotype was originally used to refer to both the trait/character itself (e.g. the blue eyes phenotype) and the set of traits/characteristics possessed by the organism (clair's ...

  4. Sonic hedgehog protein - Wikipedia

    en.wikipedia.org/wiki/Sonic_hedgehog_protein

    The brain and eyes, for example, can be significantly impacted by mutations in this gene and cause disorders such as Microphthalmia and Holoprosencephaly. [39] Microphthalmia is a condition that affects the eyes, which results in small, underdeveloped tissues in one or both eyes. [ 39 ]

  5. Leber's hereditary optic neuropathy - Wikipedia

    en.wikipedia.org/wiki/Leber's_hereditary_optic...

    Leber's hereditary optic neuropathy (LHON) is a mitochondrially inherited (transmitted from mother to offspring) degeneration of retinal ganglion cells (RGCs) and their axons that leads to an acute or subacute loss of central vision; it predominantly affects adult males, and onset is more likely in younger adults.

  6. Stargardt disease - Wikipedia

    en.wikipedia.org/wiki/Stargardt_disease

    Gene therapy is designed to insert a copy of a corrected gene into retinal cells. The hope is to return cell function back to normal and the treatment has the potential to stop disease progression. This therapy will not restore impaired vision back to normal. The research is being undertaken by a partnership between Sanofi and Oxford BioMedica.

  7. Dichromacy - Wikipedia

    en.wikipedia.org/wiki/Dichromacy

    Dichromacy (from Greek di, meaning "two" and chromo, meaning "color") is the state of having two types of functioning photoreceptors, called cone cells, in the eyes. Organisms with dichromacy are called dichromats. Dichromats require only two primary colors to be able to represent their visible gamut.

  8. Waardenburg syndrome - Wikipedia

    en.wikipedia.org/wiki/Waardenburg_syndrome

    Waardenburg syndrome is a group of rare genetic conditions characterised by at least some degree of congenital hearing loss and pigmentation deficiencies, which can include bright blue eyes (or one blue eye and one brown eye), a white forelock or patches of light skin.

  9. Monochromacy - Wikipedia

    en.wikipedia.org/wiki/Monochromacy

    Monochromacy (from Greek mono, meaning "one" and chromo, meaning "color") is the ability of organisms to perceive only light intensity without respect to spectral composition. Organisms with monochromacy lack color vision and can only see in shades of grey ranging from black to white. Organisms with monochromacy are called monochromats.